Alora

What it is

Alora is a brand-name 17β-estradiol matrix patch applied to the lower abdomen and changed twice weekly.

Available in 0.025, 0.05, 0.075, and 0.1 mg/day.

How it works

Delivers estradiol through the skin into circulation, bypassing the liver — lower clot risk than oral estrogen.

Continuous delivery smooths the hormone curve compared to oral dosing.

Who it's for

• Women under 60 or within 10 years of menopause with vasomotor symptoms
• Patients preferring a small, discreet patch
• Standard transdermal estradiol candidates

Who should not take it

• Estrogen-sensitive cancer history
• Recent clot, stroke, or MI
• Active liver disease
• Unexplained vaginal bleeding

Common side effects

• Mild patch-site redness or itching
• Breast tenderness, headache early on
• Spotting on combined therapy

Evidence summary

• FDA-approved for moderate-to-severe vasomotor symptoms and vulvar/vaginal atrophy.
• Transdermal route preferred for patients with elevated VTE risk (NAMS 2022).

Brand-name vs compounded

Alora is an FDA-approved brand-name product. Many Kindr patients use compounded alternatives prepared by a state-licensed 503A pharmacy when a custom dose, custom combination, or different delivery form is clinically preferable. Both pathways are available through Kindr — your provider will recommend based on your individual needs.

FAQ

Sources

• NAMS 2022 Hormone Therapy Position Statement
• U.S. Food & Drug Administration

Other medications

This page is educational and is not a substitute for a clinical evaluation. Whether any medication is appropriate for you depends on your full medical history. Kindr providers make individualized prescribing decisions during a clinical visit.