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Peptides shop · PHCKRM · Reference sheet

PHCKRM

Reference sheet · Signaling · CPC catalog code AOXP-001

Identity

Name
PHCKRM
Catalog code
AOXP-001
Category
Signaling

Physicochemical properties

Class
Signaling
Form
Lyophilized powder
Grade
Research use only (RUO)

Full physicochemical data (sequence, molecular formula, molecular weight, CAS) is documented on the upstream certificate of analysis. Request the current lot COA from the supplier before use — values may vary between manufacturing runs.

Handling, storage & reconstitution

General guidance for this class

Reference standards in the Signaling class are typically shipped as lyophilized powder and stored desiccated at −20 °C protected from light. Once reconstituted in bacteriostatic water or the assay-appropriate buffer, aliquot and store at −80 °C to minimize freeze–thaw cycles. Confirm handling requirements against your institutional biosafety and radiation protocols before use.

Mechanism & research applications

PHCKRM sits within the Signaling research class (CPC reference AOXP-001). Signaling peptides mimic recognition motifs (phosphotyrosine motifs, PDZ ligands, kinase docking sites) or interfere with protein–protein interactions inside the cell, allowing focused perturbation of a single node in a pathway. Investigators typically incorporate PHCKRM as a reference standard, tool ligand, or substrate in the assay contexts listed above. SPR, BLI, AlphaScreen, and pulldown / Western readouts.

Studied for

  • Protein–protein interaction (PPI) mapping
  • SH2, SH3, PDZ, and 14-3-3 binding studies
  • Allosteric modulator and PPI-inhibitor discovery
  • Signal-pathway dissection in cellular models

Frequently asked

What is PHCKRM?

PHCKRM (CPC catalog code AOXP-001) is a synthetic cell-signaling research peptide in the signaling category. It is provided as a lyophilized ~1 mg vial for in-vitro research use only.

What is PHCKRM studied for?

Published and internal research programs use PHCKRM as a reference standard in signaling workflows — for example, protein–protein interaction (ppi) mapping and sh2, sh3, pdz, and 14-3-3 binding studies. Human clinical evidence is not established.

Is PHCKRM FDA-approved for human use?

No. PHCKRM is a research-grade reference peptide and is not approved by the FDA or any national regulator for human or veterinary therapeutic use. It is offered exclusively for in-vitro laboratory research and does not ship to the United States for consumer use.

How is PHCKRM typically used in the lab?

In a signaling workflow, PHCKRM is reconstituted in sterile buffer or DMSO (solubility-dependent) and applied in the researcher's chosen assay format. SPR, BLI, AlphaScreen, and pulldown / Western readouts.

Sources

View full product page →Back to catalog

Related peptides in Signaling

Other reference standards in the same class — commonly cross-referenced during assay design and comparator selection.

T-R-N-Y-Y-V-R-A-V-L
P-F-T-R-N-Y-Y-V-R-A-V-L-H-L
Head activator
IL-8 Inhibitor
Research use only. The peptides referenced on this page are supplied to qualified laboratories for in-vitro or non-human research. They are not drugs, foods, cosmetics, or dietary supplements, are not for human consumption, and are not intended to diagnose, treat, cure, or prevent any disease. Physicochemical values shown here are transcribed from the cited upstream reference sheet(s); confirm with your own certificate of analysis before use.
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