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Peptides shop · [Lys(Me2)370]-p53 (361-380); p53K370Me2 · Reference sheet

[Lys(Me2)370]-p53 (361-380); p53K370Me2

Reference sheet · Oncology · CPC catalog code CANC-011

Identity

Name
[Lys(Me2)370]-p53 (361-380); p53K370Me2
Catalog code
CANC-011
Category
Oncology

Physicochemical properties

Class
Oncology
Form
Lyophilized powder
Grade
Research use only (RUO)

Full physicochemical data (sequence, molecular formula, molecular weight, CAS) is documented on the upstream certificate of analysis. Request the current lot COA from the supplier before use — values may vary between manufacturing runs.

Handling, storage & reconstitution

General guidance for this class

Reference standards in the Oncology class are typically shipped as lyophilized powder and stored desiccated at −20 °C protected from light. Once reconstituted in bacteriostatic water or the assay-appropriate buffer, aliquot and store at −80 °C to minimize freeze–thaw cycles. Confirm handling requirements against your institutional biosafety and radiation protocols before use.

Mechanism & research applications

[Lys(Me2)370]-p53 (361-380); p53K370Me2 sits within the Oncology research class (CPC reference CANC-011). Oncology peptides serve as tumor-targeting ligands (RGD, bombesin, somatostatin analogues), pro-apoptotic mimetics (BH3), or antigenic epitopes for T-cell recognition. Effects are read out in cell viability, receptor binding, and tumor-model contexts. Investigators typically incorporate [Lys(Me2)370]-p53 (361-380); p53K370Me2 as a reference standard, tool ligand, or substrate in the assay contexts listed above. MTT / CellTiter-Glo viability, caspase-3/7 activation, and receptor-binding SPR.

Studied for

  • Receptor-targeted drug-delivery research
  • Apoptosis and cell-viability assays
  • Tumor antigen and neoantigen studies
  • Cancer-immunology and TCR-T screening

Frequently asked

What is [Lys(Me2)370]-p53 (361-380); p53K370Me2?

[Lys(Me2)370]-p53 (361-380); p53K370Me2 (CPC catalog code CANC-011) is a synthetic oncology research peptide in the oncology category. It is provided as a lyophilized ~1 mg vial for in-vitro research use only.

What is [Lys(Me2)370]-p53 (361-380); p53K370Me2 studied for?

Published and internal research programs use [Lys(Me2)370]-p53 (361-380); p53K370Me2 as a reference standard in oncology workflows — for example, receptor-targeted drug-delivery research and apoptosis and cell-viability assays. Human clinical evidence is not established.

Is [Lys(Me2)370]-p53 (361-380); p53K370Me2 FDA-approved for human use?

No. [Lys(Me2)370]-p53 (361-380); p53K370Me2 is a research-grade reference peptide and is not approved by the FDA or any national regulator for human or veterinary therapeutic use. It is offered exclusively for in-vitro laboratory research and does not ship to the United States for consumer use.

How is [Lys(Me2)370]-p53 (361-380); p53K370Me2 typically used in the lab?

In a oncology workflow, [Lys(Me2)370]-p53 (361-380); p53K370Me2 is reconstituted in sterile buffer or DMSO (solubility-dependent) and applied in the researcher's chosen assay format. MTT / CellTiter-Glo viability, caspase-3/7 activation, and receptor-binding SPR.

Sources

View full product page →Back to catalog

Related peptides in Oncology

Other reference standards in the same class — commonly cross-referenced during assay design and comparator selection.

[Lys(Me3)370]-p53 (361-380); p53K370Me3
[Lys(Me2)382]-p53 (377-387); p53K382Me2
[Lys(Me1)382]-p53 (377-387); p53K382Me1
[Lys(Me3)382]-p53 (377-387); p53K382Me3
p53 Tumor Suppressor (361-393), human
[Lys(Ac)382]-p53 (372-389), biotin labeled
[Lys(Ac)382]-p53 (374-389); p53 acetylated K382
Research use only. The peptides referenced on this page are supplied to qualified laboratories for in-vitro or non-human research. They are not drugs, foods, cosmetics, or dietary supplements, are not for human consumption, and are not intended to diagnose, treat, cure, or prevent any disease. Physicochemical values shown here are transcribed from the cited upstream reference sheet(s); confirm with your own certificate of analysis before use.
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