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Peptides shop · (Trp63,Trp64)-C3a (63-77) · Reference sheet

(Trp63,Trp64)-C3a (63-77)

Reference sheet · Bone / Cartilage · CPC catalog code COMA-001

Identity

Name
(Trp63,Trp64)-C3a (63-77)
Catalog code
COMA-001
Category
Bone / Cartilage

Physicochemical properties

Sequence
H-Trp-Trp-Gly-Lys-Lys-Tyr-Arg-Ala-Ser-Lys-Leu-Gly-Leu-Ala-Arg-OH (trifluoroacetate salt)

Handling, storage & reconstitution

Upstream storage
CONDITIONS:**-20 ± 5 °C

General guidance for this class

Reference standards in the Bone / Cartilage class are typically shipped as lyophilized powder and stored desiccated at −20 °C protected from light. Once reconstituted in bacteriostatic water or the assay-appropriate buffer, aliquot and store at −80 °C to minimize freeze–thaw cycles. Confirm handling requirements against your institutional biosafety and radiation protocols before use.

Mechanism & research applications

(Trp63,Trp64)-C3a (63-77) sits within the Bone / Cartilage research class (CPC reference COMA-001). These peptides interact with bone- and cartilage-relevant receptors and matrix proteins — including RANK/RANKL, PTH1R, integrins, and collagen-binding motifs — modulating osteoblast, osteoclast, and chondrocyte activity in cellular and organ-culture models. Investigators typically incorporate (Trp63,Trp64)-C3a (63-77) as a reference standard, tool ligand, or substrate in the assay contexts listed above. Commonly paired with ALP, TRAP, or Alizarin Red staining in cell-based readouts.

Studied for

  • Osteoblast / osteoclast differentiation assays
  • Chondrocyte and cartilage-explant remodeling studies
  • Bone-resorption and mineralization models
  • Biomaterial functionalization for orthopaedic scaffolds

Frequently asked

What is (Trp63,Trp64)-C3a (63-77)?

(Trp63,Trp64)-C3a (63-77) (CPC catalog code COMA-001) is a synthetic bone / cartilage biology peptide in the bone / cartilage category. It is provided as a lyophilized ~1 mg vial for in-vitro research use only.

What is (Trp63,Trp64)-C3a (63-77) studied for?

Published and internal research programs use (Trp63,Trp64)-C3a (63-77) as a reference standard in bone / cartilage workflows — for example, osteoblast / osteoclast differentiation assays and chondrocyte and cartilage-explant remodeling studies. Human clinical evidence is not established.

Is (Trp63,Trp64)-C3a (63-77) FDA-approved for human use?

No. (Trp63,Trp64)-C3a (63-77) is a research-grade reference peptide and is not approved by the FDA or any national regulator for human or veterinary therapeutic use. It is offered exclusively for in-vitro laboratory research and does not ship to the United States for consumer use.

How is (Trp63,Trp64)-C3a (63-77) typically used in the lab?

In a bone / cartilage workflow, (Trp63,Trp64)-C3a (63-77) is reconstituted in sterile buffer or DMSO (solubility-dependent) and applied in the researcher's chosen assay format. Commonly paired with ALP, TRAP, or Alizarin Red staining in cell-based readouts.

Sources

View full product page →Back to catalog

Related peptides in Bone / Cartilage

Other reference standards in the same class — commonly cross-referenced during assay design and comparator selection.

Osteocalcin (1-49), human
Osteogenic Growth Peptide
Osteostatin amide (human)
Osteocalcin (37-49), human
Bone Gla Protein (45-49)
Parathyroid Hormone (1-13)
Myelopeptide-2 (MP-2)
Research use only. The peptides referenced on this page are supplied to qualified laboratories for in-vitro or non-human research. They are not drugs, foods, cosmetics, or dietary supplements, are not for human consumption, and are not intended to diagnose, treat, cure, or prevent any disease. Physicochemical values shown here are transcribed from the cited upstream reference sheet(s); confirm with your own certificate of analysis before use.
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