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Peptides shop · DPDPE · Reference sheet

DPDPE

Reference sheet · Opioid · CPC catalog code ENKP-001

Identity

Name
DPDPE
Catalog code
ENKP-001
Category
Opioid

Physicochemical properties

Sequence
H-Tyr-DPen-Gly-Phe-DPen-OH (trifluoroacetate salt)

Handling, storage & reconstitution

Upstream storage
CONDITIONS:**-20 ± 5 °C

General guidance for this class

Reference standards in the Opioid class are typically shipped as lyophilized powder and stored desiccated at −20 °C protected from light. Once reconstituted in bacteriostatic water or the assay-appropriate buffer, aliquot and store at −80 °C to minimize freeze–thaw cycles. Confirm handling requirements against your institutional biosafety and radiation protocols before use.

Mechanism & research applications

DPDPE sits within the Opioid research class (CPC reference ENKP-001). Opioid peptides bind μ, δ, and κ receptors — Gi/o-coupled GPCRs that inhibit adenylate cyclase, activate GIRK channels, and modulate calcium currents to produce analgesia, tolerance, and reward-circuit effects. Investigators typically incorporate DPDPE as a reference standard, tool ligand, or substrate in the assay contexts listed above. GTPγS binding, cAMP HTRF, and β-arrestin PathHunter assays.

Studied for

  • Opioid-receptor binding and selectivity profiling
  • β-arrestin recruitment and biased-agonism studies
  • Analgesic mechanism research
  • Tolerance and dependence models

Frequently asked

What is DPDPE?

DPDPE (CPC catalog code ENKP-001) is a synthetic opioid-receptor research peptide in the opioid category. It is provided as a lyophilized ~1 mg vial for in-vitro research use only.

What is DPDPE studied for?

Published and internal research programs use DPDPE as a reference standard in opioid workflows — for example, opioid-receptor binding and selectivity profiling and β-arrestin recruitment and biased-agonism studies. Human clinical evidence is not established.

Is DPDPE FDA-approved for human use?

No. DPDPE is a research-grade reference peptide and is not approved by the FDA or any national regulator for human or veterinary therapeutic use. It is offered exclusively for in-vitro laboratory research and does not ship to the United States for consumer use.

How is DPDPE typically used in the lab?

In a opioid workflow, DPDPE is reconstituted in sterile buffer or DMSO (solubility-dependent) and applied in the researcher's chosen assay format. GTPγS binding, cAMP HTRF, and β-arrestin PathHunter assays.

Sources

View full product page →Back to catalog

Related peptides in Opioid

Other reference standards in the same class — commonly cross-referenced during assay design and comparator selection.

Met-Enkephalin
[DPen2, Pen5] Enkephalin
[Des-Tyr1,DPen2,5] Enkephalin
[DPhe2,5,(pCl)Phe4] Enkephalin
[Des-Tyr1,DPen2,Pen5] Enkephalin
Research use only. The peptides referenced on this page are supplied to qualified laboratories for in-vitro or non-human research. They are not drugs, foods, cosmetics, or dietary supplements, are not for human consumption, and are not intended to diagnose, treat, cure, or prevent any disease. Physicochemical values shown here are transcribed from the cited upstream reference sheet(s); confirm with your own certificate of analysis before use.
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