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Reference sheet · Endocrine · CPC catalog code GAST-001
Full physicochemical data (sequence, molecular formula, molecular weight, CAS) is documented on the upstream certificate of analysis. Request the current lot COA from the supplier before use — values may vary between manufacturing runs.
Reference standards in the Endocrine class are typically shipped as lyophilized powder and stored desiccated at −20 °C protected from light. Once reconstituted in bacteriostatic water or the assay-appropriate buffer, aliquot and store at −80 °C to minimize freeze–thaw cycles. Confirm handling requirements against your institutional biosafety and radiation protocols before use.
Big Gastrin 1, human sits within the Endocrine research class (CPC reference GAST-001). Endocrine peptides bind class A/B GPCRs and RTKs on hormone-responsive tissues, triggering canonical cAMP, IP₃/Ca²⁺, and MAPK pathways that regulate secretion, growth, and metabolism. Investigators typically incorporate Big Gastrin 1, human as a reference standard, tool ligand, or substrate in the assay contexts listed above. HTRF cAMP, calcium mobilization (FLIPR), and radioligand binding are the standard readouts.
Big Gastrin 1, human (CPC catalog code GAST-001) is a synthetic endocrine research peptide in the endocrine category. It is provided as a lyophilized ~1 mg vial for in-vitro research use only.
Published and internal research programs use Big Gastrin 1, human as a reference standard in endocrine workflows — for example, receptor-binding and functional selectivity studies and second-messenger (camp / ip₁) profiling. Human clinical evidence is not established.
No. Big Gastrin 1, human is a research-grade reference peptide and is not approved by the FDA or any national regulator for human or veterinary therapeutic use. It is offered exclusively for in-vitro laboratory research and does not ship to the United States for consumer use.
In a endocrine workflow, Big Gastrin 1, human is reconstituted in sterile buffer or DMSO (solubility-dependent) and applied in the researcher's chosen assay format. HTRF cAMP, calcium mobilization (FLIPR), and radioligand binding are the standard readouts.
Other reference standards in the same class — commonly cross-referenced during assay design and comparator selection.