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Peptides shop · Mca-Gly-Ala-Lys(Ac)-Arg-His-Arg-Lys-Val-NH2 · Reference sheet

Mca-Gly-Ala-Lys(Ac)-Arg-His-Arg-Lys-Val-NH2

Reference sheet · Histone / Epigenetic · CPC catalog code HIST-008

Identity

Name
Mca-Gly-Ala-Lys(Ac)-Arg-His-Arg-Lys-Val-NH2
Catalog code
HIST-008
Category
Histone / Epigenetic

Physicochemical properties

Sequence
MCA-Gly-Ala-Lys(Ac)-Arg-His-Arg-Lys-Val-NH2 (trifluoroacetate salt)

Handling, storage & reconstitution

Upstream storage
CONDITIONS:**-20 ± 5 °C

General guidance for this class

Reference standards in the Histone / Epigenetic class are typically shipped as lyophilized powder and stored desiccated at −20 °C protected from light. Once reconstituted in bacteriostatic water or the assay-appropriate buffer, aliquot and store at −80 °C to minimize freeze–thaw cycles. Confirm handling requirements against your institutional biosafety and radiation protocols before use.

Mechanism & research applications

Mca-Gly-Ala-Lys(Ac)-Arg-His-Arg-Lys-Val-NH2 sits within the Histone / Epigenetic research class (CPC reference HIST-008). These peptides carry defined post-translational modifications (methylation, acetylation, phosphorylation) at N-terminal histone tail residues, allowing biochemical characterization of writers (HMTs, HATs), erasers (KDMs, HDACs), and readers (bromodomains, chromodomains). Investigators typically incorporate Mca-Gly-Ala-Lys(Ac)-Arg-His-Arg-Lys-Val-NH2 as a reference standard, tool ligand, or substrate in the assay contexts listed above. SPR / BLI binding, AlphaScreen, TR-FRET, and MS-based activity assays.

Studied for

  • HAT / HDAC / HMT / KDM activity assays
  • Bromodomain and chromodomain binding studies
  • Epigenetic inhibitor screening
  • Chromatin-mark specificity profiling

Frequently asked

What is Mca-Gly-Ala-Lys(Ac)-Arg-His-Arg-Lys-Val-NH2?

Mca-Gly-Ala-Lys(Ac)-Arg-His-Arg-Lys-Val-NH2 (CPC catalog code HIST-008) is a synthetic histone / epigenetic reader-writer substrate in the histone / epigenetic category. It is provided as a lyophilized ~1 mg vial for in-vitro research use only.

What is Mca-Gly-Ala-Lys(Ac)-Arg-His-Arg-Lys-Val-NH2 studied for?

Published and internal research programs use Mca-Gly-Ala-Lys(Ac)-Arg-His-Arg-Lys-Val-NH2 as a reference standard in histone / epigenetic workflows — for example, hat / hdac / hmt / kdm activity assays and bromodomain and chromodomain binding studies. Human clinical evidence is not established.

Is Mca-Gly-Ala-Lys(Ac)-Arg-His-Arg-Lys-Val-NH2 FDA-approved for human use?

No. Mca-Gly-Ala-Lys(Ac)-Arg-His-Arg-Lys-Val-NH2 is a research-grade reference peptide and is not approved by the FDA or any national regulator for human or veterinary therapeutic use. It is offered exclusively for in-vitro laboratory research and does not ship to the United States for consumer use.

How is Mca-Gly-Ala-Lys(Ac)-Arg-His-Arg-Lys-Val-NH2 typically used in the lab?

In a histone / epigenetic workflow, Mca-Gly-Ala-Lys(Ac)-Arg-His-Arg-Lys-Val-NH2 is reconstituted in sterile buffer or DMSO (solubility-dependent) and applied in the researcher's chosen assay format. SPR / BLI binding, AlphaScreen, TR-FRET, and MS-based activity assays.

Sources

View full product page →Back to catalog

Related peptides in Histone / Epigenetic

Other reference standards in the same class — commonly cross-referenced during assay design and comparator selection.

Abz-Gly-Ala-Lys(Ac)-Ala-Ala-Dap(Dnp)-NH2
Ac-Gly-Ala-Lys(Ac)-AMC
[Lys(Ac)9]-Histone H3 (1-20), H3K9(Ac)
[Lys(Ac)9]-Histone H3 (1-21), H3K9(Ac)
[Lys(Ac)9]-Histone H3 (1-24), H3K9(Ac)
[Lys(Ac)12]-Histone H2B (1-22)-GGK(Biotin)-NH2; H2BK12(Ac), biotin-labeled
[Lys(Me1)27]-Histone H3 (23-34), H3K27(Me1)
[Lys(Me2)27]-Histone H3 (23-34), H3K27(Me2)
Research use only. The peptides referenced on this page are supplied to qualified laboratories for in-vitro or non-human research. They are not drugs, foods, cosmetics, or dietary supplements, are not for human consumption, and are not intended to diagnose, treat, cure, or prevent any disease. Physicochemical values shown here are transcribed from the cited upstream reference sheet(s); confirm with your own certificate of analysis before use.
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