We value your privacy

We use cookies to analyze site usage and improve your experience. You can accept all, reject non-essential, or customize. See our Privacy Policy.

kindr currently serves patients in the United States only. Content is for informational purposes elsewhere.
Peptides shop · K(biotin)-W-Histone H2B (108-125); H2B, N-Terminal biotin-labeled · Reference sheet

K(biotin)-W-Histone H2B (108-125); H2B, N-Terminal biotin-labeled

Reference sheet · Histone / Epigenetic · CPC catalog code HIST-017

Identity

Name
K(biotin)-W-Histone H2B (108-125); H2B, N-Terminal biotin-labeled
Catalog code
HIST-017
Category
Histone / Epigenetic

Physicochemical properties

Sequence
H-Lys(Biotin)-Trp-Lys-His-Ala-Val-Ser-Glu-Gly-Thr-Lys-Ala-Val-Thr-Lys-Tyr-Thr-Ser-Ser-Lys-OH (trifluoroacetate salt)

Handling, storage & reconstitution

Upstream storage
CONDITIONS:**-20 ± 5 °C

General guidance for this class

Reference standards in the Histone / Epigenetic class are typically shipped as lyophilized powder and stored desiccated at −20 °C protected from light. Once reconstituted in bacteriostatic water or the assay-appropriate buffer, aliquot and store at −80 °C to minimize freeze–thaw cycles. Confirm handling requirements against your institutional biosafety and radiation protocols before use.

Mechanism & research applications

K(biotin)-W-Histone H2B (108-125); H2B, N-Terminal biotin-labeled sits within the Histone / Epigenetic research class (CPC reference HIST-017). These peptides carry defined post-translational modifications (methylation, acetylation, phosphorylation) at N-terminal histone tail residues, allowing biochemical characterization of writers (HMTs, HATs), erasers (KDMs, HDACs), and readers (bromodomains, chromodomains). Investigators typically incorporate K(biotin)-W-Histone H2B (108-125); H2B, N-Terminal biotin-labeled as a reference standard, tool ligand, or substrate in the assay contexts listed above. SPR / BLI binding, AlphaScreen, TR-FRET, and MS-based activity assays.

Studied for

  • HAT / HDAC / HMT / KDM activity assays
  • Bromodomain and chromodomain binding studies
  • Epigenetic inhibitor screening
  • Chromatin-mark specificity profiling

Frequently asked

What is K(biotin)-W-Histone H2B (108-125); H2B, N-Terminal biotin-labeled?

K(biotin)-W-Histone H2B (108-125); H2B, N-Terminal biotin-labeled (CPC catalog code HIST-017) is a synthetic histone / epigenetic reader-writer substrate in the histone / epigenetic category. It is provided as a lyophilized ~1 mg vial for in-vitro research use only.

What is K(biotin)-W-Histone H2B (108-125); H2B, N-Terminal biotin-labeled studied for?

Published and internal research programs use K(biotin)-W-Histone H2B (108-125); H2B, N-Terminal biotin-labeled as a reference standard in histone / epigenetic workflows — for example, hat / hdac / hmt / kdm activity assays and bromodomain and chromodomain binding studies. Human clinical evidence is not established.

Is K(biotin)-W-Histone H2B (108-125); H2B, N-Terminal biotin-labeled FDA-approved for human use?

No. K(biotin)-W-Histone H2B (108-125); H2B, N-Terminal biotin-labeled is a research-grade reference peptide and is not approved by the FDA or any national regulator for human or veterinary therapeutic use. It is offered exclusively for in-vitro laboratory research and does not ship to the United States for consumer use.

How is K(biotin)-W-Histone H2B (108-125); H2B, N-Terminal biotin-labeled typically used in the lab?

In a histone / epigenetic workflow, K(biotin)-W-Histone H2B (108-125); H2B, N-Terminal biotin-labeled is reconstituted in sterile buffer or DMSO (solubility-dependent) and applied in the researcher's chosen assay format. SPR / BLI binding, AlphaScreen, TR-FRET, and MS-based activity assays.

Sources

View full product page →Back to catalog

Related peptides in Histone / Epigenetic

Other reference standards in the same class — commonly cross-referenced during assay design and comparator selection.

Histone H2B (21-41), biotin labeled
[Lys(Ac)12]-Histone H2B (1-22)-GGK(Biotin)-NH2; H2BK12(Ac), biotin-labeled
Histone H3 (21-44)-GK(Biotin), biotin-labeled, amide
Histone H3 (21-44)-GK(Biotin), biotin-labeled
[Lys(Ac)27]-Histone 3 (21-44)-GK(Biotin); H3K27(Ac), biotin-labeled
[Lys(Me1)27]-Histone H3 (15-39)-K(Biotin), H3K27(Me1), biotin-labeled
[Lys(Ac)27]-Histone H3 (21-43)-GGK(Biotin), H3K27(Ac), biotin-labeled
[Lys(Me3)36]-Histone H3 (26-46)-K(Biotin), H3K36(Me3), biotin labeled
Research use only. The peptides referenced on this page are supplied to qualified laboratories for in-vitro or non-human research. They are not drugs, foods, cosmetics, or dietary supplements, are not for human consumption, and are not intended to diagnose, treat, cure, or prevent any disease. Physicochemical values shown here are transcribed from the cited upstream reference sheet(s); confirm with your own certificate of analysis before use.
Ask Dot