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Reference sheet · Histone / Epigenetic · CPC catalog code HIST-079
Reference standards in the Histone / Epigenetic class are typically shipped as lyophilized powder and stored desiccated at −20 °C protected from light. Once reconstituted in bacteriostatic water or the assay-appropriate buffer, aliquot and store at −80 °C to minimize freeze–thaw cycles. Confirm handling requirements against your institutional biosafety and radiation protocols before use.
AKT/PKB/Rac-Protein Kinase Substrate [ARKRERTYSFGHHA] sits within the Histone / Epigenetic research class (CPC reference HIST-079). These peptides carry defined post-translational modifications (methylation, acetylation, phosphorylation) at N-terminal histone tail residues, allowing biochemical characterization of writers (HMTs, HATs), erasers (KDMs, HDACs), and readers (bromodomains, chromodomains). Investigators typically incorporate AKT/PKB/Rac-Protein Kinase Substrate [ARKRERTYSFGHHA] as a reference standard, tool ligand, or substrate in the assay contexts listed above. SPR / BLI binding, AlphaScreen, TR-FRET, and MS-based activity assays.
AKT/PKB/Rac-Protein Kinase Substrate [ARKRERTYSFGHHA] (CPC catalog code HIST-079) is a synthetic histone / epigenetic reader-writer substrate in the histone / epigenetic category. It is provided as a lyophilized ~1 mg vial for in-vitro research use only.
Published and internal research programs use AKT/PKB/Rac-Protein Kinase Substrate [ARKRERTYSFGHHA] as a reference standard in histone / epigenetic workflows — for example, hat / hdac / hmt / kdm activity assays and bromodomain and chromodomain binding studies. Human clinical evidence is not established.
No. AKT/PKB/Rac-Protein Kinase Substrate [ARKRERTYSFGHHA] is a research-grade reference peptide and is not approved by the FDA or any national regulator for human or veterinary therapeutic use. It is offered exclusively for in-vitro laboratory research and does not ship to the United States for consumer use.
In a histone / epigenetic workflow, AKT/PKB/Rac-Protein Kinase Substrate [ARKRERTYSFGHHA] is reconstituted in sterile buffer or DMSO (solubility-dependent) and applied in the researcher's chosen assay format. SPR / BLI binding, AlphaScreen, TR-FRET, and MS-based activity assays.
Other reference standards in the same class — commonly cross-referenced during assay design and comparator selection.