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Peptides shop · Leupeptin · Reference sheet

Leupeptin

Reference sheet · Growth Factors · CPC catalog code LEUP-001

Identity

Name
Leupeptin
Catalog code
LEUP-001
Category
Growth Factors

Physicochemical properties

Sequence
Ac-Leu-Leu-Arg-CHO (trifluoroacetate salt)

Handling, storage & reconstitution

Upstream storage
CONDITIONS:**-20 ± 5 °C

General guidance for this class

Reference standards in the Growth Factors class are typically shipped as lyophilized powder and stored desiccated at −20 °C protected from light. Once reconstituted in bacteriostatic water or the assay-appropriate buffer, aliquot and store at −80 °C to minimize freeze–thaw cycles. Confirm handling requirements against your institutional biosafety and radiation protocols before use.

Mechanism & research applications

Leupeptin sits within the Growth Factors research class (CPC reference LEUP-001). Growth-factor peptides activate receptor tyrosine kinases (EGFR, FGFR, VEGFR, IGF-1R) and downstream RAS–MAPK and PI3K–AKT pathways that drive proliferation, migration, and survival. Investigators typically incorporate Leupeptin as a reference standard, tool ligand, or substrate in the assay contexts listed above. Phospho-ERK and phospho-AKT Western blots or AlphaLISA assays are the standard readouts.

Studied for

  • Proliferation and BrdU / EdU assays
  • Wound-healing and scratch-closure models
  • Angiogenesis (tube-formation, aortic ring) studies
  • Regenerative-medicine and stem-cell differentiation work

Frequently asked

What is Leupeptin?

Leupeptin (CPC catalog code LEUP-001) is a synthetic growth-factor / mitogen peptide in the growth factors category. It is provided as a lyophilized ~1 mg vial for in-vitro research use only.

What is Leupeptin studied for?

Published and internal research programs use Leupeptin as a reference standard in growth factors workflows — for example, proliferation and brdu / edu assays and wound-healing and scratch-closure models. Human clinical evidence is not established.

Is Leupeptin FDA-approved for human use?

No. Leupeptin is a research-grade reference peptide and is not approved by the FDA or any national regulator for human or veterinary therapeutic use. It is offered exclusively for in-vitro laboratory research and does not ship to the United States for consumer use.

How is Leupeptin typically used in the lab?

In a growth factors workflow, Leupeptin is reconstituted in sterile buffer or DMSO (solubility-dependent) and applied in the researcher's chosen assay format. Phospho-ERK and phospho-AKT Western blots or AlphaLISA assays are the standard readouts.

Sources

View full product page →Back to catalog

Related peptides in Growth Factors

Other reference standards in the same class — commonly cross-referenced during assay design and comparator selection.

IGF-II (33-40)
Insulin B (22-25)
KGF Receptor Peptide
2-Furoyl-LIGRL-Amide
Research use only. The peptides referenced on this page are supplied to qualified laboratories for in-vitro or non-human research. They are not drugs, foods, cosmetics, or dietary supplements, are not for human consumption, and are not intended to diagnose, treat, cure, or prevent any disease. Physicochemical values shown here are transcribed from the cited upstream reference sheet(s); confirm with your own certificate of analysis before use.
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