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Peptides shop · LH-RH, Free Acid · Reference sheet

LH-RH, Free Acid

Reference sheet · Endocrine · CPC catalog code LHRH-002

Identity

Name
LH-RH, Free Acid
Catalog code
LHRH-002
Category
Endocrine

Physicochemical properties

Sequence
Glp-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-OH (trifluoroacetate salt)

Handling, storage & reconstitution

Upstream storage
CONDITIONS:**-20 ± 5 °C

General guidance for this class

Reference standards in the Endocrine class are typically shipped as lyophilized powder and stored desiccated at −20 °C protected from light. Once reconstituted in bacteriostatic water or the assay-appropriate buffer, aliquot and store at −80 °C to minimize freeze–thaw cycles. Confirm handling requirements against your institutional biosafety and radiation protocols before use.

Mechanism & research applications

LH-RH, Free Acid sits within the Endocrine research class (CPC reference LHRH-002). Endocrine peptides bind class A/B GPCRs and RTKs on hormone-responsive tissues, triggering canonical cAMP, IP₃/Ca²⁺, and MAPK pathways that regulate secretion, growth, and metabolism. Investigators typically incorporate LH-RH, Free Acid as a reference standard, tool ligand, or substrate in the assay contexts listed above. HTRF cAMP, calcium mobilization (FLIPR), and radioligand binding are the standard readouts.

Studied for

  • Receptor-binding and functional selectivity studies
  • Second-messenger (cAMP / IP₁) profiling
  • Hypothalamic–pituitary axis feedback modeling
  • Metabolic and glucose-homeostasis research

Frequently asked

What is LH-RH, Free Acid?

LH-RH, Free Acid (CPC catalog code LHRH-002) is a synthetic endocrine research peptide in the endocrine category. It is provided as a lyophilized ~1 mg vial for in-vitro research use only.

What is LH-RH, Free Acid studied for?

Published and internal research programs use LH-RH, Free Acid as a reference standard in endocrine workflows — for example, receptor-binding and functional selectivity studies and second-messenger (camp / ip₁) profiling. Human clinical evidence is not established.

Is LH-RH, Free Acid FDA-approved for human use?

No. LH-RH, Free Acid is a research-grade reference peptide and is not approved by the FDA or any national regulator for human or veterinary therapeutic use. It is offered exclusively for in-vitro laboratory research and does not ship to the United States for consumer use.

How is LH-RH, Free Acid typically used in the lab?

In a endocrine workflow, LH-RH, Free Acid is reconstituted in sterile buffer or DMSO (solubility-dependent) and applied in the researcher's chosen assay format. HTRF cAMP, calcium mobilization (FLIPR), and radioligand binding are the standard readouts.

Sources

View full product page →Back to catalog

Related peptides in Endocrine

Other reference standards in the same class — commonly cross-referenced during assay design and comparator selection.

LH-RH, lamprey
[Des-Gly10, DTrp6],Pro-NHEt9)-LH-RH
[DTrp6]-LH-RH Triptoreline, Ethyl Amide
Buserelin-NHNH2
LHRH (chicken)
Research use only. The peptides referenced on this page are supplied to qualified laboratories for in-vitro or non-human research. They are not drugs, foods, cosmetics, or dietary supplements, are not for human consumption, and are not intended to diagnose, treat, cure, or prevent any disease. Physicochemical values shown here are transcribed from the cited upstream reference sheet(s); confirm with your own certificate of analysis before use.
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