We value your privacy

We use cookies to analyze site usage and improve your experience. You can accept all, reject non-essential, or customize. See our Privacy Policy.

kindr currently serves patients in the United States only. Content is for informational purposes elsewhere.
Peptides shop · Luteinizing Hormone-Releasing Hormone Antagonist · Reference sheet

Luteinizing Hormone-Releasing Hormone Antagonist

Reference sheet · Endocrine · CPC catalog code LHRH-021

Identity

Name
Luteinizing Hormone-Releasing Hormone Antagonist
Catalog code
LHRH-021
Category
Endocrine

Physicochemical properties

Sequence
Ac-D-2-Nal-p-chloro-D-Phe-beta-(3-pyridyl)-D-Ala-Gly-Arg-Pro-D-Ala-NH2 (trifluoroacetate salt)

Handling, storage & reconstitution

Upstream storage
CONDITIONS:**-20 ± 5 °C

General guidance for this class

Reference standards in the Endocrine class are typically shipped as lyophilized powder and stored desiccated at −20 °C protected from light. Once reconstituted in bacteriostatic water or the assay-appropriate buffer, aliquot and store at −80 °C to minimize freeze–thaw cycles. Confirm handling requirements against your institutional biosafety and radiation protocols before use.

Mechanism & research applications

Luteinizing Hormone-Releasing Hormone Antagonist sits within the Endocrine research class (CPC reference LHRH-021). Endocrine peptides bind class A/B GPCRs and RTKs on hormone-responsive tissues, triggering canonical cAMP, IP₃/Ca²⁺, and MAPK pathways that regulate secretion, growth, and metabolism. Investigators typically incorporate Luteinizing Hormone-Releasing Hormone Antagonist as a reference standard, tool ligand, or substrate in the assay contexts listed above. HTRF cAMP, calcium mobilization (FLIPR), and radioligand binding are the standard readouts.

Studied for

  • Receptor-binding and functional selectivity studies
  • Second-messenger (cAMP / IP₁) profiling
  • Hypothalamic–pituitary axis feedback modeling
  • Metabolic and glucose-homeostasis research

Frequently asked

What is Luteinizing Hormone-Releasing Hormone Antagonist?

Luteinizing Hormone-Releasing Hormone Antagonist (CPC catalog code LHRH-021) is a synthetic endocrine research peptide in the endocrine category. It is provided as a lyophilized ~1 mg vial for in-vitro research use only.

What is Luteinizing Hormone-Releasing Hormone Antagonist studied for?

Published and internal research programs use Luteinizing Hormone-Releasing Hormone Antagonist as a reference standard in endocrine workflows — for example, receptor-binding and functional selectivity studies and second-messenger (camp / ip₁) profiling. Human clinical evidence is not established.

Is Luteinizing Hormone-Releasing Hormone Antagonist FDA-approved for human use?

No. Luteinizing Hormone-Releasing Hormone Antagonist is a research-grade reference peptide and is not approved by the FDA or any national regulator for human or veterinary therapeutic use. It is offered exclusively for in-vitro laboratory research and does not ship to the United States for consumer use.

How is Luteinizing Hormone-Releasing Hormone Antagonist typically used in the lab?

In a endocrine workflow, Luteinizing Hormone-Releasing Hormone Antagonist is reconstituted in sterile buffer or DMSO (solubility-dependent) and applied in the researcher's chosen assay format. HTRF cAMP, calcium mobilization (FLIPR), and radioligand binding are the standard readouts.

Sources

View full product page →Back to catalog

Related peptides in Endocrine

Other reference standards in the same class — commonly cross-referenced during assay design and comparator selection.

Growth Hormone Pro-Releasing Factor, human
[DTrp6]-LH-RH Triptoreline, Ethyl Amide
Acetyl-(D-Trp1,4-chloro-D-Phe2,D-Trp3,D-Arg6,D-Ala10)-LHRH
[Des-Gly10, DTrp6],Pro-NHEt9)-LH-RH
Thyrotropin Releasing Hormone, TRH (Human, Ovine, Porcine, Rat)
LH-RH, Free Acid
Buserelin-NHNH2
LH-RH, lamprey
Research use only. The peptides referenced on this page are supplied to qualified laboratories for in-vitro or non-human research. They are not drugs, foods, cosmetics, or dietary supplements, are not for human consumption, and are not intended to diagnose, treat, cure, or prevent any disease. Physicochemical values shown here are transcribed from the cited upstream reference sheet(s); confirm with your own certificate of analysis before use.
Ask Dot