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Reference sheet · Kinase Substrates · CPC catalog code PKCP-054
Full physicochemical data (sequence, molecular formula, molecular weight, CAS) is documented on the upstream certificate of analysis. Request the current lot COA from the supplier before use — values may vary between manufacturing runs.
Reference standards in the Kinase Substrates class are typically shipped as lyophilized powder and stored desiccated at −20 °C protected from light. Once reconstituted in bacteriostatic water or the assay-appropriate buffer, aliquot and store at −80 °C to minimize freeze–thaw cycles. Confirm handling requirements against your institutional biosafety and radiation protocols before use.
Tyr-Ser-Phe-Val-His-His-Gly-Phe-Phe-Asn-Phe-Arg-Val-Ser-Trp-Arg-Glu-Met-Leu-Ala sits within the Kinase Substrates research class (CPC reference PKCP-054). These peptides carry consensus phosphorylation motifs recognized by specific kinase families (PKA, PKC, CDK, MAPK, tyrosine kinases). Phosphorylation is detected via radiolabel incorporation, ADP quantitation, or antibody-based readouts. Investigators typically incorporate Tyr-Ser-Phe-Val-His-His-Gly-Phe-Phe-Asn-Phe-Arg-Val-Ser-Trp-Arg-Glu-Met-Leu-Ala as a reference standard, tool ligand, or substrate in the assay contexts listed above. ADP-Glo, HTRF KinEASE, and radiometric filter-binding assays.
Tyr-Ser-Phe-Val-His-His-Gly-Phe-Phe-Asn-Phe-Arg-Val-Ser-Trp-Arg-Glu-Met-Leu-Ala (CPC catalog code PKCP-054) is a synthetic kinase / phosphatase substrate in the kinase substrates category. It is provided as a lyophilized ~1 mg vial for in-vitro research use only.
Published and internal research programs use Tyr-Ser-Phe-Val-His-His-Gly-Phe-Phe-Asn-Phe-Arg-Val-Ser-Trp-Arg-Glu-Met-Leu-Ala as a reference standard in kinase substrates workflows — for example, kinase activity and kinetic characterization and high-throughput inhibitor screening. Human clinical evidence is not established.
No. Tyr-Ser-Phe-Val-His-His-Gly-Phe-Phe-Asn-Phe-Arg-Val-Ser-Trp-Arg-Glu-Met-Leu-Ala is a research-grade reference peptide and is not approved by the FDA or any national regulator for human or veterinary therapeutic use. It is offered exclusively for in-vitro laboratory research and does not ship to the United States for consumer use.
In a kinase substrates workflow, Tyr-Ser-Phe-Val-His-His-Gly-Phe-Phe-Asn-Phe-Arg-Val-Ser-Trp-Arg-Glu-Met-Leu-Ala is reconstituted in sterile buffer or DMSO (solubility-dependent) and applied in the researcher's chosen assay format. ADP-Glo, HTRF KinEASE, and radiometric filter-binding assays.
Other reference standards in the same class — commonly cross-referenced during assay design and comparator selection.