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Peptides shop · JAG-1 (188-204), Jagged-1 (188-204), Notch Ligand, DSL Peptide · Reference sheet

JAG-1 (188-204), Jagged-1 (188-204), Notch Ligand, DSL Peptide

Reference sheet · Signaling · CPC catalog code SIGN-009

Identity

Name
JAG-1 (188-204), Jagged-1 (188-204), Notch Ligand, DSL Peptide
Catalog code
SIGN-009
Category
Signaling

Physicochemical properties

Sequence
H-Cys-Asp-Asp-Tyr-Tyr-Tyr-Gly-Phe-Gly-Cys-Asn-Lys-Phe-Cys-Arg-Pro-Arg-OH (trifluoroacetate salt)

Handling, storage & reconstitution

Upstream storage
CONDITIONS:**-20 ± 5 °C

General guidance for this class

Reference standards in the Signaling class are typically shipped as lyophilized powder and stored desiccated at −20 °C protected from light. Once reconstituted in bacteriostatic water or the assay-appropriate buffer, aliquot and store at −80 °C to minimize freeze–thaw cycles. Confirm handling requirements against your institutional biosafety and radiation protocols before use.

Mechanism & research applications

JAG-1 (188-204), Jagged-1 (188-204), Notch Ligand, DSL Peptide sits within the Signaling research class (CPC reference SIGN-009). Signaling peptides mimic recognition motifs (phosphotyrosine motifs, PDZ ligands, kinase docking sites) or interfere with protein–protein interactions inside the cell, allowing focused perturbation of a single node in a pathway. Investigators typically incorporate JAG-1 (188-204), Jagged-1 (188-204), Notch Ligand, DSL Peptide as a reference standard, tool ligand, or substrate in the assay contexts listed above. SPR, BLI, AlphaScreen, and pulldown / Western readouts.

Studied for

  • Protein–protein interaction (PPI) mapping
  • SH2, SH3, PDZ, and 14-3-3 binding studies
  • Allosteric modulator and PPI-inhibitor discovery
  • Signal-pathway dissection in cellular models

Frequently asked

What is JAG-1 (188-204), Jagged-1 (188-204), Notch Ligand, DSL Peptide?

JAG-1 (188-204), Jagged-1 (188-204), Notch Ligand, DSL Peptide (CPC catalog code SIGN-009) is a synthetic cell-signaling research peptide in the signaling category. It is provided as a lyophilized ~1 mg vial for in-vitro research use only.

What is JAG-1 (188-204), Jagged-1 (188-204), Notch Ligand, DSL Peptide studied for?

Published and internal research programs use JAG-1 (188-204), Jagged-1 (188-204), Notch Ligand, DSL Peptide as a reference standard in signaling workflows — for example, protein–protein interaction (ppi) mapping and sh2, sh3, pdz, and 14-3-3 binding studies. Human clinical evidence is not established.

Is JAG-1 (188-204), Jagged-1 (188-204), Notch Ligand, DSL Peptide FDA-approved for human use?

No. JAG-1 (188-204), Jagged-1 (188-204), Notch Ligand, DSL Peptide is a research-grade reference peptide and is not approved by the FDA or any national regulator for human or veterinary therapeutic use. It is offered exclusively for in-vitro laboratory research and does not ship to the United States for consumer use.

How is JAG-1 (188-204), Jagged-1 (188-204), Notch Ligand, DSL Peptide typically used in the lab?

In a signaling workflow, JAG-1 (188-204), Jagged-1 (188-204), Notch Ligand, DSL Peptide is reconstituted in sterile buffer or DMSO (solubility-dependent) and applied in the researcher's chosen assay format. SPR, BLI, AlphaScreen, and pulldown / Western readouts.

Sources

View full product page →Back to catalog

Related peptides in Signaling

Other reference standards in the same class — commonly cross-referenced during assay design and comparator selection.

Calmodulin-Dependent Protein Kinase I (299-320) Binding Domain
Steroid Receptor Coactivator-1 (SRC-1), (676-700), biotin labeled
M13 Skeletal Muscle Myosin Light Chain Kinase Peptide, SK-MLCK M13
WRW4, Formyl Peptide Receptor-Like 1 (FPRL1) Antagonist
TET 830 modified/T-helper epitope from tetanus toxoid
SmMLCKp, Smooth-Muscle Myosin Light-Chain Kinase (796-815), Calmodulin Binding
Pannexin-1 (Panx1), Mimetic Blocking Peptide
eNOS (494-513), Calmodulin Binding Domain
Research use only. The peptides referenced on this page are supplied to qualified laboratories for in-vitro or non-human research. They are not drugs, foods, cosmetics, or dietary supplements, are not for human consumption, and are not intended to diagnose, treat, cure, or prevent any disease. Physicochemical values shown here are transcribed from the cited upstream reference sheet(s); confirm with your own certificate of analysis before use.
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