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Peptides shop · DOTA-Octreotide · Reference sheet

DOTA-Octreotide

Reference sheet · Endocrine · CPC catalog code SOMA-015

Identity

Name
DOTA-Octreotide
Catalog code
SOMA-015
Category
Endocrine

Physicochemical properties

Sequence
DOTA-DPhe-Cys-Phe-DTrp-Lys-Thr-Cys-Thr-ol (trifluoroacetate salt) (Cys2 and 7 bridge)

Handling, storage & reconstitution

Upstream storage
CONDITIONS:**-20 ± 5 °C

General guidance for this class

Reference standards in the Endocrine class are typically shipped as lyophilized powder and stored desiccated at −20 °C protected from light. Once reconstituted in bacteriostatic water or the assay-appropriate buffer, aliquot and store at −80 °C to minimize freeze–thaw cycles. Confirm handling requirements against your institutional biosafety and radiation protocols before use.

Mechanism & research applications

DOTA-Octreotide sits within the Endocrine research class (CPC reference SOMA-015). Endocrine peptides bind class A/B GPCRs and RTKs on hormone-responsive tissues, triggering canonical cAMP, IP₃/Ca²⁺, and MAPK pathways that regulate secretion, growth, and metabolism. Investigators typically incorporate DOTA-Octreotide as a reference standard, tool ligand, or substrate in the assay contexts listed above. HTRF cAMP, calcium mobilization (FLIPR), and radioligand binding are the standard readouts.

Studied for

  • Receptor-binding and functional selectivity studies
  • Second-messenger (cAMP / IP₁) profiling
  • Hypothalamic–pituitary axis feedback modeling
  • Metabolic and glucose-homeostasis research

Frequently asked

What is DOTA-Octreotide?

DOTA-Octreotide (CPC catalog code SOMA-015) is a synthetic endocrine research peptide in the endocrine category. It is provided as a lyophilized ~1 mg vial for in-vitro research use only.

What is DOTA-Octreotide studied for?

Published and internal research programs use DOTA-Octreotide as a reference standard in endocrine workflows — for example, receptor-binding and functional selectivity studies and second-messenger (camp / ip₁) profiling. Human clinical evidence is not established.

Is DOTA-Octreotide FDA-approved for human use?

No. DOTA-Octreotide is a research-grade reference peptide and is not approved by the FDA or any national regulator for human or veterinary therapeutic use. It is offered exclusively for in-vitro laboratory research and does not ship to the United States for consumer use.

How is DOTA-Octreotide typically used in the lab?

In a endocrine workflow, DOTA-Octreotide is reconstituted in sterile buffer or DMSO (solubility-dependent) and applied in the researcher's chosen assay format. HTRF cAMP, calcium mobilization (FLIPR), and radioligand binding are the standard readouts.

Sources

View full product page →Back to catalog

Related peptides in Endocrine

Other reference standards in the same class — commonly cross-referenced during assay design and comparator selection.

DOTA-[Tyr3]-Octreotide
DOTA-(Tyr3)-Octreotate
Octreotide (SMS 201-995)
Somatostatin 14
NTB (Naltriben)
Somatostatin 28
RC-160 (Vapreotide)
Somatostatin 28 (1-14)
Research use only. The peptides referenced on this page are supplied to qualified laboratories for in-vitro or non-human research. They are not drugs, foods, cosmetics, or dietary supplements, are not for human consumption, and are not intended to diagnose, treat, cure, or prevent any disease. Physicochemical values shown here are transcribed from the cited upstream reference sheet(s); confirm with your own certificate of analysis before use.
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