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Peptides shop · HIV-1 TAT Protein Peptide · Reference sheet

HIV-1 TAT Protein Peptide

Reference sheet · Cell-Penetrating · CPC catalog code TAT-002

Identity

Name
HIV-1 TAT Protein Peptide
Catalog code
TAT-002
Category
Cell-Penetrating

Physicochemical properties

Sequence
H-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-OH (trifluoroacetate salt)

Handling, storage & reconstitution

Upstream storage
CONDITIONS:**-20 ± 5 °C

General guidance for this class

Reference standards in the Cell-Penetrating class are typically shipped as lyophilized powder and stored desiccated at −20 °C protected from light. Once reconstituted in bacteriostatic water or the assay-appropriate buffer, aliquot and store at −80 °C to minimize freeze–thaw cycles. Confirm handling requirements against your institutional biosafety and radiation protocols before use.

Mechanism & research applications

HIV-1 TAT Protein Peptide sits within the Cell-Penetrating research class (CPC reference TAT-002). CPPs cross cellular membranes through energy-independent direct translocation and/or endocytic uptake driven by cationic residues (arginine-rich sequences) or amphipathic architecture. They are typically conjugated to a cargo of interest. Investigators typically incorporate HIV-1 TAT Protein Peptide as a reference standard, tool ligand, or substrate in the assay contexts listed above. Fluorescent-conjugate flow cytometry and confocal imaging are the standard uptake readouts.

Studied for

  • Intracellular cargo delivery (peptides, siRNA, proteins)
  • Endosomal-escape and trafficking studies
  • In vitro screens of CPP variants for uptake efficiency
  • Structure–activity work on cationic / amphipathic CPPs

Frequently asked

What is HIV-1 TAT Protein Peptide?

HIV-1 TAT Protein Peptide (CPC catalog code TAT-002) is a synthetic cell-penetrating peptide (cpp) in the cell-penetrating category. It is provided as a lyophilized ~1 mg vial for in-vitro research use only.

What is HIV-1 TAT Protein Peptide studied for?

Published and internal research programs use HIV-1 TAT Protein Peptide as a reference standard in cell-penetrating workflows — for example, intracellular cargo delivery (peptides, sirna, proteins) and endosomal-escape and trafficking studies. Human clinical evidence is not established.

Is HIV-1 TAT Protein Peptide FDA-approved for human use?

No. HIV-1 TAT Protein Peptide is a research-grade reference peptide and is not approved by the FDA or any national regulator for human or veterinary therapeutic use. It is offered exclusively for in-vitro laboratory research and does not ship to the United States for consumer use.

How is HIV-1 TAT Protein Peptide typically used in the lab?

In a cell-penetrating workflow, HIV-1 TAT Protein Peptide is reconstituted in sterile buffer or DMSO (solubility-dependent) and applied in the researcher's chosen assay format. Fluorescent-conjugate flow cytometry and confocal imaging are the standard uptake readouts.

Sources

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Related peptides in Cell-Penetrating

Other reference standards in the same class — commonly cross-referenced during assay design and comparator selection.

HIV-1 tat Protein (1-9)
Ala-Leu-Ala-Leu
HIV-1 tat Protein (49-57)
HIV-1 rev Protein (34-50)
HIV-1 gag Protein p17 (76-84)
HIV (gp41) Fragment
Research use only. The peptides referenced on this page are supplied to qualified laboratories for in-vitro or non-human research. They are not drugs, foods, cosmetics, or dietary supplements, are not for human consumption, and are not intended to diagnose, treat, cure, or prevent any disease. Physicochemical values shown here are transcribed from the cited upstream reference sheet(s); confirm with your own certificate of analysis before use.
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