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Peptides shop · Tau Peptide (337-368) (Repeat 4 domain) · Reference sheet

Tau Peptide (337-368) (Repeat 4 domain)

Reference sheet · Neurodegenerative · CPC catalog code TAUP-006

Identity

Name
Tau Peptide (337-368) (Repeat 4 domain)
Catalog code
TAUP-006
Category
Neurodegenerative

Physicochemical properties

Sequence
H-Val-Glu-Val-Lys-Ser-Glu-Lys-Leu-Asp-Phe-Lys-Asp-Arg-Val-Gln-Ser-Lys-Ile-Gly-Ser-Leu-Asp-Asn-Ile-Thr-His-Val-Pro-Gly-Gly-Gly-Asn-OH (trifluoroacetate salt)

Handling, storage & reconstitution

Upstream storage
CONDITIONS:**-20 ± 5 °C

General guidance for this class

Reference standards in the Neurodegenerative class are typically shipped as lyophilized powder and stored desiccated at −20 °C protected from light. Once reconstituted in bacteriostatic water or the assay-appropriate buffer, aliquot and store at −80 °C to minimize freeze–thaw cycles. Confirm handling requirements against your institutional biosafety and radiation protocols before use.

Mechanism & research applications

Tau Peptide (337-368) (Repeat 4 domain) sits within the Neurodegenerative research class (CPC reference TAUP-006). These peptides (amyloid-β, α-synuclein, tau, prion fragments) form ordered β-sheet aggregates and oligomeric species that are used to interrogate seeding, propagation, and cellular toxicity mechanisms of neurodegeneration. Investigators typically incorporate Tau Peptide (337-368) (Repeat 4 domain) as a reference standard, tool ligand, or substrate in the assay contexts listed above. ThT fluorescence, AFM / TEM morphology, and neuronal-toxicity readouts (LDH, MTT).

Studied for

  • Aggregation kinetics (ThT, ANS fluorescence) studies
  • Oligomer- and fibril-mediated toxicity assays
  • Seeding and prion-like propagation models
  • Aggregation-inhibitor and antibody screening

Frequently asked

What is Tau Peptide (337-368) (Repeat 4 domain)?

Tau Peptide (337-368) (Repeat 4 domain) (CPC catalog code TAUP-006) is a synthetic neurodegenerative-disease research peptide in the neurodegenerative category. It is provided as a lyophilized ~1 mg vial for in-vitro research use only.

What is Tau Peptide (337-368) (Repeat 4 domain) studied for?

Published and internal research programs use Tau Peptide (337-368) (Repeat 4 domain) as a reference standard in neurodegenerative workflows — for example, aggregation kinetics (tht, ans fluorescence) studies and oligomer- and fibril-mediated toxicity assays. Human clinical evidence is not established.

Is Tau Peptide (337-368) (Repeat 4 domain) FDA-approved for human use?

No. Tau Peptide (337-368) (Repeat 4 domain) is a research-grade reference peptide and is not approved by the FDA or any national regulator for human or veterinary therapeutic use. It is offered exclusively for in-vitro laboratory research and does not ship to the United States for consumer use.

How is Tau Peptide (337-368) (Repeat 4 domain) typically used in the lab?

In a neurodegenerative workflow, Tau Peptide (337-368) (Repeat 4 domain) is reconstituted in sterile buffer or DMSO (solubility-dependent) and applied in the researcher's chosen assay format. ThT fluorescence, AFM / TEM morphology, and neuronal-toxicity readouts (LDH, MTT).

Sources

View full product page →Back to catalog

Related peptides in Neurodegenerative

Other reference standards in the same class — commonly cross-referenced during assay design and comparator selection.

Tau Peptide (244-274) (Repeat 1 domain)
Tau Peptide (275-305) (Repeat 2 domain)
Tau Peptide (306-336) (Repeat 3 domain)
Tau Peptide (45-73) (Exon 2/Insert 1 domain)
Tau Peptide (74-102) (Exon 3/Insert 2 domain)
beta-Secretase Substrate I, Fluorogenic
alpha-Secretase Substrate I, Fluorogenic
Amyloid BRI Protein (1-34) (reduced)
Research use only. The peptides referenced on this page are supplied to qualified laboratories for in-vitro or non-human research. They are not drugs, foods, cosmetics, or dietary supplements, are not for human consumption, and are not intended to diagnose, treat, cure, or prevent any disease. Physicochemical values shown here are transcribed from the cited upstream reference sheet(s); confirm with your own certificate of analysis before use.
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