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Peptides shop · RGD-4C · Reference sheet

RGD-4C

Reference sheet · Coagulation · CPC catalog code THRO-005

Identity

Name
RGD-4C
Catalog code
THRO-005
Category
Coagulation

Physicochemical properties

Sequence
Ala-Cys-Asp-Cys-Arg-Gly-Asp-Cys-Phe-Cys-Gly (Cys2 and Cys10, Cys4 and Cys8 bridge) (trifluoroacetate salt)

Handling, storage & reconstitution

Upstream storage
CONDITIONS:**-20 ± 5 °C

General guidance for this class

Reference standards in the Coagulation class are typically shipped as lyophilized powder and stored desiccated at −20 °C protected from light. Once reconstituted in bacteriostatic water or the assay-appropriate buffer, aliquot and store at −80 °C to minimize freeze–thaw cycles. Confirm handling requirements against your institutional biosafety and radiation protocols before use.

Mechanism & research applications

RGD-4C sits within the Coagulation research class (CPC reference THRO-005). Coagulation peptides act either as chromogenic / fluorogenic substrates for thrombin, FXa, FVIIa, plasmin, and related proteases, or as inhibitors and receptor ligands (e.g. PAR-1/4 activators) that dissect specific cascade nodes. Investigators typically incorporate RGD-4C as a reference standard, tool ligand, or substrate in the assay contexts listed above. Read on kinetic plate readers at 405 nm (pNA) or fluorescence (AMC / MCA) endpoints.

Studied for

  • Chromogenic protease-activity assays
  • PAR (protease-activated receptor) signaling studies
  • Antithrombotic and anticoagulant screening
  • Fibrinolysis and clot-lysis kinetics

Frequently asked

What is RGD-4C?

RGD-4C (CPC catalog code THRO-005) is a synthetic coagulation cascade peptide / substrate in the coagulation category. It is provided as a lyophilized ~1 mg vial for in-vitro research use only.

What is RGD-4C studied for?

Published and internal research programs use RGD-4C as a reference standard in coagulation workflows — for example, chromogenic protease-activity assays and par (protease-activated receptor) signaling studies. Human clinical evidence is not established.

Is RGD-4C FDA-approved for human use?

No. RGD-4C is a research-grade reference peptide and is not approved by the FDA or any national regulator for human or veterinary therapeutic use. It is offered exclusively for in-vitro laboratory research and does not ship to the United States for consumer use.

How is RGD-4C typically used in the lab?

In a coagulation workflow, RGD-4C is reconstituted in sterile buffer or DMSO (solubility-dependent) and applied in the researcher's chosen assay format. Read on kinetic plate readers at 405 nm (pNA) or fluorescence (AMC / MCA) endpoints.

Sources

View full product page →Back to catalog

Related peptides in Coagulation

Other reference standards in the same class — commonly cross-referenced during assay design and comparator selection.

Prototype of RGD-containing peptide, FITC-labeled
Hexahydro peptide
Thrombin substrate
Hemoglobin (Hb) (64-76)
Scrambled TRAP Fragment
Thrombin Receptor Peptide Ligand
Thrombin Sensitive Peptide (Acid)
Research use only. The peptides referenced on this page are supplied to qualified laboratories for in-vitro or non-human research. They are not drugs, foods, cosmetics, or dietary supplements, are not for human consumption, and are not intended to diagnose, treat, cure, or prevent any disease. Physicochemical values shown here are transcribed from the cited upstream reference sheet(s); confirm with your own certificate of analysis before use.
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