Metabolic · Metabolic peptide (research)
AICAR
- Drug class
- Metabolic peptide (research)
- Status
- Compounded (503A)
- Also known as
- acadesine, aica riboside, ampk activator
- Reviewed
- 2026-06-01 · Dr. Ana Lisa Carr, MD
What AICAR is studied for
- AMPK activation (research)
- Endurance research (research)
- Glucose uptake (research)
Mechanism of action
AICAR is being studied in the metabolic category. AMPK activator studied for endurance and metabolic efficiency. Mechanism of action varies by study model; refer to the kindr clinical library for a deeper writeup.
Frequently asked questions
What is AICAR?
AICAR is a metabolic peptide. AMPK activator studied for endurance and metabolic efficiency.
What is AICAR studied for?
Published research has examined AICAR for ampk activation, endurance research, glucose uptake. Human clinical evidence varies by indication.
Is AICAR FDA-approved?
No. AICAR is not FDA-approved for the indications listed. It is available compounded by 503A pharmacies under clinician supervision, or for international research use only on this catalog.
How is AICAR used in research?
Protocols vary by study. AICAR is typically administered subcutaneously in research settings. No validated human therapeutic dose exists outside FDA-approved indications.
What are the known risks?
Long-term human safety data for AICAR is limited. Theoretical risks vary by mechanism. Any human use should be supervised by a licensed clinician.