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Enzyme Substrates · Enzyme substrate (research reagent) · CASB-001

Calpain Substrate

Research use · ships internationally
$85.00 / 1mg vial
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Calpain Substrate reference vial
Drug class
Enzyme substrate (research reagent)
Status
Research use only
Catalog code
CASB-001
Also known as
CASB-001
Reviewed
2026-06-01 · Kindr Health Clinical Team

What Calpain Substrate is studied for

  • Kinetic (kcat / Km) characterization of proteases and hydrolases
  • High-throughput inhibitor screening
  • Selectivity profiling across related enzyme families
  • Diagnostic and academic activity assays

Mechanism of action

Calpain Substrate sits within the Enzyme Substrates research class (CPC reference CASB-001). The peptide encodes a recognition sequence flanked by a reporter group (pNA, AMC, MCA, FAM/DABCYL). Enzyme cleavage releases the reporter, producing a quantifiable optical signal proportional to catalytic activity. Investigators typically incorporate Calpain Substrate as a reference standard, tool ligand, or substrate in the assay contexts listed above. Read on kinetic plate readers with the reporter-appropriate filter set (e.g. 405 nm, 380/460 nm).

Frequently asked questions

What is Calpain Substrate?

Calpain Substrate (CPC catalog code CASB-001) is a synthetic enzyme substrate (research reagent) in the enzyme substrates category. It is provided as a lyophilized ~1 mg vial for in-vitro research use only.

What is Calpain Substrate studied for?

Published and internal research programs use Calpain Substrate as a reference standard in enzyme substrates workflows — for example, kinetic (kcat / km) characterization of proteases and hydrolases and high-throughput inhibitor screening. Human clinical evidence is not established.

Is Calpain Substrate FDA-approved for human use?

No. Calpain Substrate is a research-grade reference peptide and is not approved by the FDA or any national regulator for human or veterinary therapeutic use. It is offered exclusively for in-vitro laboratory research and does not ship to the United States for consumer use.

How is Calpain Substrate typically used in the lab?

In a enzyme substrates workflow, Calpain Substrate is reconstituted in sterile buffer or DMSO (solubility-dependent) and applied in the researcher's chosen assay format. Read on kinetic plate readers with the reporter-appropriate filter set (e.g. 405 nm, 380/460 nm).

How should Calpain Substrate be stored?

Store lyophilized at −20 °C, protected from light. DMSO stocks stable at −80 °C for months. Follow your institution's standard operating procedures for handling synthetic peptides.

Where does the Calpain Substrate product page point to?

This kindr reference page mirrors CPC Scientific's catalog metadata for CASB-001. The upstream reference sheet — including sequence, purity, MW, and application notes where published — is linked from the buy panel. All orders placed on kindr Peptides ship internationally under research-use terms only.

What quality specifications apply to Calpain Substrate?

Research-grade peptides in the CPC catalog are synthesized by solid-phase peptide synthesis (SPPS), purified by preparative RP-HPLC, and characterized by analytical HPLC and mass spectrometry. Typical purity is ≥95%; certificate of analysis is available on request.

Internal reference sheetOpen the Calpain Substrate physicochemical & handling reference →Upstream reference sheetView CPC Scientific catalog page for CASB-001 →Add to cart · International research catalogBuy Calpain Substrate in the kindr Peptides Shop →

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Research & medical disclosure. This page is educational reference content reviewed by a licensed physician. It is not medical advice and does not establish a clinician–patient relationship. Peptides offered on the kindr Peptides Shop are sold for in vitro laboratory research purposes only and ship internationally — not to the United States. For U.S. clinical care, use the kindr Longevity intake.