Enzyme Substrates · Enzyme substrate (research reagent) · CASP-049
Apopain Substrate
- Drug class
- Enzyme substrate (research reagent)
- Status
- Research use only
- Catalog code
- CASP-049
- Also known as
- CASP-049
- Reviewed
- 2026-06-01 · Kindr Health Clinical Team
What Apopain Substrate is studied for
- Kinetic (kcat / Km) characterization of proteases and hydrolases
- High-throughput inhibitor screening
- Selectivity profiling across related enzyme families
- Diagnostic and academic activity assays
Mechanism of action
Apopain Substrate sits within the Enzyme Substrates research class (CPC reference CASP-049). The peptide encodes a recognition sequence flanked by a reporter group (pNA, AMC, MCA, FAM/DABCYL). Enzyme cleavage releases the reporter, producing a quantifiable optical signal proportional to catalytic activity. Investigators typically incorporate Apopain Substrate as a reference standard, tool ligand, or substrate in the assay contexts listed above. Read on kinetic plate readers with the reporter-appropriate filter set (e.g. 405 nm, 380/460 nm).
Frequently asked questions
What is Apopain Substrate?
Apopain Substrate (CPC catalog code CASP-049) is a synthetic enzyme substrate (research reagent) in the enzyme substrates category. It is provided as a lyophilized ~1 mg vial for in-vitro research use only.
What is Apopain Substrate studied for?
Published and internal research programs use Apopain Substrate as a reference standard in enzyme substrates workflows — for example, kinetic (kcat / km) characterization of proteases and hydrolases and high-throughput inhibitor screening. Human clinical evidence is not established.
Is Apopain Substrate FDA-approved for human use?
No. Apopain Substrate is a research-grade reference peptide and is not approved by the FDA or any national regulator for human or veterinary therapeutic use. It is offered exclusively for in-vitro laboratory research and does not ship to the United States for consumer use.
How is Apopain Substrate typically used in the lab?
In a enzyme substrates workflow, Apopain Substrate is reconstituted in sterile buffer or DMSO (solubility-dependent) and applied in the researcher's chosen assay format. Read on kinetic plate readers with the reporter-appropriate filter set (e.g. 405 nm, 380/460 nm).
How should Apopain Substrate be stored?
Store lyophilized at −20 °C, protected from light. DMSO stocks stable at −80 °C for months. Follow your institution's standard operating procedures for handling synthetic peptides.
Where does the Apopain Substrate product page point to?
This kindr reference page mirrors CPC Scientific's catalog metadata for CASP-049. The upstream reference sheet — including sequence, purity, MW, and application notes where published — is linked from the buy panel. All orders placed on kindr Peptides ship internationally under research-use terms only.
What quality specifications apply to Apopain Substrate?
Research-grade peptides in the CPC catalog are synthesized by solid-phase peptide synthesis (SPPS), purified by preparative RP-HPLC, and characterized by analytical HPLC and mass spectrometry. Typical purity is ≥95%; certificate of analysis is available on request.
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