Protease Substrates · Protease substrate (research reagent) · CATI-001
GEGFLGfL
- Drug class
- Protease substrate (research reagent)
- Status
- Research use only
- Catalog code
- CATI-001
- Also known as
- CATI-001
- Reviewed
- 2026-06-01 · Kindr Health Clinical Team
What GEGFLGfL is studied for
- Kinetic (kcat / Km) protease characterization
- Inhibitor screening and IC₅₀ determination
- Selectivity profiling across protease families
- Cell-based and diagnostic activity assays
Mechanism of action
GEGFLGfL sits within the Protease Substrates research class (CPC reference CATI-001). The peptide encodes a specific protease-recognition motif flanked by a reporter (pNA, AMC, MCA / Dnp FRET pair). Enzymatic cleavage releases the reporter, producing signal directly proportional to catalytic activity. Investigators typically incorporate GEGFLGfL as a reference standard, tool ligand, or substrate in the assay contexts listed above. Read on kinetic plate readers at the reporter-appropriate wavelength.
Frequently asked questions
What is GEGFLGfL?
GEGFLGfL (CPC catalog code CATI-001) is a synthetic protease substrate (research reagent) in the protease substrates category. It is provided as a lyophilized ~1 mg vial for in-vitro research use only.
What is GEGFLGfL studied for?
Published and internal research programs use GEGFLGfL as a reference standard in protease substrates workflows — for example, kinetic (kcat / km) protease characterization and inhibitor screening and ic₅₀ determination. Human clinical evidence is not established.
Is GEGFLGfL FDA-approved for human use?
No. GEGFLGfL is a research-grade reference peptide and is not approved by the FDA or any national regulator for human or veterinary therapeutic use. It is offered exclusively for in-vitro laboratory research and does not ship to the United States for consumer use.
How is GEGFLGfL typically used in the lab?
In a protease substrates workflow, GEGFLGfL is reconstituted in sterile buffer or DMSO (solubility-dependent) and applied in the researcher's chosen assay format. Read on kinetic plate readers at the reporter-appropriate wavelength.
How should GEGFLGfL be stored?
Store lyophilized at −20 °C, protected from light. DMSO stocks stable at −80 °C. Follow your institution's standard operating procedures for handling synthetic peptides.
Where does the GEGFLGfL product page point to?
This kindr reference page mirrors CPC Scientific's catalog metadata for CATI-001. The upstream reference sheet — including sequence, purity, MW, and application notes where published — is linked from the buy panel. All orders placed on kindr Peptides ship internationally under research-use terms only.
What quality specifications apply to GEGFLGfL?
Research-grade peptides in the CPC catalog are synthesized by solid-phase peptide synthesis (SPPS), purified by preparative RP-HPLC, and characterized by analytical HPLC and mass spectrometry. Typical purity is ≥95%; certificate of analysis is available on request.
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