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Ion Channel Toxins · Ion-channel toxin (research reagent) · CHAT-001

Charybdotoxin

Research use · ships internationally
$140.00 / 1mg vial
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Charybdotoxin reference vial
Drug class
Ion-channel toxin (research reagent)
Status
Research use only
Catalog code
CHAT-001
Also known as
CHAT-001
Reviewed
2026-06-01 · Kindr Health Clinical Team

What Charybdotoxin is studied for

  • Patch-clamp characterization of channel subtypes
  • Neuronal excitability and pain-circuit research
  • Cardiac electrophysiology and arrhythmia models
  • Structure–function mapping of channel pores

Mechanism of action

Charybdotoxin sits within the Ion Channel Toxins research class (CPC reference CHAT-001). Ion-channel toxins bind with sub-nanomolar affinity to specific channel subtypes (Kv, Nav, Cav, NMDA), stabilizing closed, open, or inactivated states. They are among the most selective tools available for dissecting channel function. Investigators typically incorporate Charybdotoxin as a reference standard, tool ligand, or substrate in the assay contexts listed above. Manual or automated patch clamp (QPatch, Patchliner) and radioligand binding are the standard readouts.

Frequently asked questions

What is Charybdotoxin?

Charybdotoxin (CPC catalog code CHAT-001) is a synthetic ion-channel toxin (research reagent) in the ion channel toxins category. It is provided as a lyophilized ~1 mg vial for in-vitro research use only.

What is Charybdotoxin studied for?

Published and internal research programs use Charybdotoxin as a reference standard in ion channel toxins workflows — for example, patch-clamp characterization of channel subtypes and neuronal excitability and pain-circuit research. Human clinical evidence is not established.

Is Charybdotoxin FDA-approved for human use?

No. Charybdotoxin is a research-grade reference peptide and is not approved by the FDA or any national regulator for human or veterinary therapeutic use. It is offered exclusively for in-vitro laboratory research and does not ship to the United States for consumer use.

How is Charybdotoxin typically used in the lab?

In a ion channel toxins workflow, Charybdotoxin is reconstituted in sterile buffer or DMSO (solubility-dependent) and applied in the researcher's chosen assay format. Manual or automated patch clamp (QPatch, Patchliner) and radioligand binding are the standard readouts.

How should Charybdotoxin be stored?

Toxins are extremely potent. Handle with appropriate PPE. Store lyophilized at −20 °C; keep reconstituted stocks in silanized tubes to prevent adsorption. Follow your institution's standard operating procedures for handling synthetic peptides.

Where does the Charybdotoxin product page point to?

This kindr reference page mirrors CPC Scientific's catalog metadata for CHAT-001. The upstream reference sheet — including sequence, purity, MW, and application notes where published — is linked from the buy panel. All orders placed on kindr Peptides ship internationally under research-use terms only.

What quality specifications apply to Charybdotoxin?

Research-grade peptides in the CPC catalog are synthesized by solid-phase peptide synthesis (SPPS), purified by preparative RP-HPLC, and characterized by analytical HPLC and mass spectrometry. Typical purity is ≥95%; certificate of analysis is available on request.

Internal reference sheetOpen the Charybdotoxin physicochemical & handling reference →Upstream reference sheetView CPC Scientific catalog page for CHAT-001 →Add to cart · International research catalogBuy Charybdotoxin in the kindr Peptides Shop →

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Research & medical disclosure. This page is educational reference content reviewed by a licensed physician. It is not medical advice and does not establish a clinician–patient relationship. Peptides offered on the kindr Peptides Shop are sold for in vitro laboratory research purposes only and ship internationally — not to the United States. For U.S. clinical care, use the kindr Longevity intake.