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Endocrine · Endocrine research peptide · CRFS-004

alpha-Helical Corticotropin Releasing Factor (9-41)

Research use · ships internationally
$90.00 / 1mg vial
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alpha-Helical Corticotropin Releasing Factor (9-41) reference vial
Drug class
Endocrine research peptide
Status
Research use only
Catalog code
CRFS-004
Also known as
CRFS-004
Reviewed
2026-06-01 · Kindr Health Clinical Team

What alpha-Helical Corticotropin Releasing Factor (9-41) is studied for

  • Receptor-binding and functional selectivity studies
  • Second-messenger (cAMP / IP₁) profiling
  • Hypothalamic–pituitary axis feedback modeling
  • Metabolic and glucose-homeostasis research

Mechanism of action

alpha-Helical Corticotropin Releasing Factor (9-41) sits within the Endocrine research class (CPC reference CRFS-004). Endocrine peptides bind class A/B GPCRs and RTKs on hormone-responsive tissues, triggering canonical cAMP, IP₃/Ca²⁺, and MAPK pathways that regulate secretion, growth, and metabolism. Investigators typically incorporate alpha-Helical Corticotropin Releasing Factor (9-41) as a reference standard, tool ligand, or substrate in the assay contexts listed above. HTRF cAMP, calcium mobilization (FLIPR), and radioligand binding are the standard readouts.

Frequently asked questions

What is alpha-Helical Corticotropin Releasing Factor (9-41)?

alpha-Helical Corticotropin Releasing Factor (9-41) (CPC catalog code CRFS-004) is a synthetic endocrine research peptide in the endocrine category. It is provided as a lyophilized ~1 mg vial for in-vitro research use only.

What is alpha-Helical Corticotropin Releasing Factor (9-41) studied for?

Published and internal research programs use alpha-Helical Corticotropin Releasing Factor (9-41) as a reference standard in endocrine workflows — for example, receptor-binding and functional selectivity studies and second-messenger (camp / ip₁) profiling. Human clinical evidence is not established.

Is alpha-Helical Corticotropin Releasing Factor (9-41) FDA-approved for human use?

No. alpha-Helical Corticotropin Releasing Factor (9-41) is a research-grade reference peptide and is not approved by the FDA or any national regulator for human or veterinary therapeutic use. It is offered exclusively for in-vitro laboratory research and does not ship to the United States for consumer use.

How is alpha-Helical Corticotropin Releasing Factor (9-41) typically used in the lab?

In a endocrine workflow, alpha-Helical Corticotropin Releasing Factor (9-41) is reconstituted in sterile buffer or DMSO (solubility-dependent) and applied in the researcher's chosen assay format. HTRF cAMP, calcium mobilization (FLIPR), and radioligand binding are the standard readouts.

How should alpha-Helical Corticotropin Releasing Factor (9-41) be stored?

Store lyophilized at −20 °C, protected from light. Reconstitute in sterile 0.1% BSA/PBS. Follow your institution's standard operating procedures for handling synthetic peptides.

Where does the alpha-Helical Corticotropin Releasing Factor (9-41) product page point to?

This kindr reference page mirrors CPC Scientific's catalog metadata for CRFS-004. The upstream reference sheet — including sequence, purity, MW, and application notes where published — is linked from the buy panel. All orders placed on kindr Peptides ship internationally under research-use terms only.

What quality specifications apply to alpha-Helical Corticotropin Releasing Factor (9-41)?

Research-grade peptides in the CPC catalog are synthesized by solid-phase peptide synthesis (SPPS), purified by preparative RP-HPLC, and characterized by analytical HPLC and mass spectrometry. Typical purity is ≥95%; certificate of analysis is available on request.

Internal reference sheetOpen the alpha-Helical Corticotropin Releasing Factor (9-41) physicochemical & handling reference →Upstream reference sheetView CPC Scientific catalog page for CRFS-004 →Add to cart · International research catalogBuy alpha-Helical Corticotropin Releasing Factor (9-41) in the kindr Peptides Shop →

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Research & medical disclosure. This page is educational reference content reviewed by a licensed physician. It is not medical advice and does not establish a clinician–patient relationship. Peptides offered on the kindr Peptides Shop are sold for in vitro laboratory research purposes only and ship internationally — not to the United States. For U.S. clinical care, use the kindr Longevity intake.