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Antimicrobial · Antimicrobial peptide (AMP) reference standard · DEFS-008

alpha-Defensin 6

Research use · ships internationally
$95.00 / 1mg vial
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alpha-Defensin 6 reference vial
Drug class
Antimicrobial peptide (AMP) reference standard
Status
Research use only
Catalog code
DEFS-008
Also known as
DEFS-008
Reviewed
2026-06-01 · Kindr Health Clinical Team

What alpha-Defensin 6 is studied for

  • Minimum inhibitory concentration (MIC) screens against Gram-positive and Gram-negative panels
  • Biofilm disruption and anti-biofilm surface coatings
  • Structure–activity relationship (SAR) studies for AMP analogues
  • Host-defense and innate-immunity mechanistic work

Mechanism of action

alpha-Defensin 6 sits within the Antimicrobial research class (CPC reference DEFS-008). Antimicrobial peptides typically disrupt bacterial, fungal, or viral membranes through direct electrostatic and hydrophobic interactions, or by triggering intracellular targets after translocation. Assay potency is usually reported as MIC (minimum inhibitory concentration) against reference strains. Investigators typically incorporate alpha-Defensin 6 as a reference standard, tool ligand, or substrate in the assay contexts listed above. Most commonly used in broth microdilution MIC assays (CLSI M07), radial diffusion assays, and membrane-permeabilization (SYTOX / DiSC₃-5) readouts.

Frequently asked questions

What is alpha-Defensin 6?

alpha-Defensin 6 (CPC catalog code DEFS-008) is a synthetic antimicrobial peptide (amp) reference standard in the antimicrobial category. It is provided as a lyophilized ~1 mg vial for in-vitro research use only.

What is alpha-Defensin 6 studied for?

Published and internal research programs use alpha-Defensin 6 as a reference standard in antimicrobial workflows — for example, minimum inhibitory concentration (mic) screens against gram-positive and gram-negative panels and biofilm disruption and anti-biofilm surface coatings. Human clinical evidence is not established.

Is alpha-Defensin 6 FDA-approved for human use?

No. alpha-Defensin 6 is a research-grade reference peptide and is not approved by the FDA or any national regulator for human or veterinary therapeutic use. It is offered exclusively for in-vitro laboratory research and does not ship to the United States for consumer use.

How is alpha-Defensin 6 typically used in the lab?

In a antimicrobial workflow, alpha-Defensin 6 is reconstituted in sterile buffer or DMSO (solubility-dependent) and applied in the researcher's chosen assay format. Most commonly used in broth microdilution MIC assays (CLSI M07), radial diffusion assays, and membrane-permeabilization (SYTOX / DiSC₃-5) readouts.

How should alpha-Defensin 6 be stored?

Lyophilized peptide is stable long-term at −20 °C. Reconstituted stock solutions are typically stored at 4 °C for short-term use or aliquoted and frozen for longer storage. Follow your institution's standard operating procedures for handling synthetic peptides.

Where does the alpha-Defensin 6 product page point to?

This kindr reference page mirrors CPC Scientific's catalog metadata for DEFS-008. The upstream reference sheet — including sequence, purity, MW, and application notes where published — is linked from the buy panel. All orders placed on kindr Peptides ship internationally under research-use terms only.

What quality specifications apply to alpha-Defensin 6?

Research-grade peptides in the CPC catalog are synthesized by solid-phase peptide synthesis (SPPS), purified by preparative RP-HPLC, and characterized by analytical HPLC and mass spectrometry. Typical purity is ≥95%; certificate of analysis is available on request.

Internal reference sheetOpen the alpha-Defensin 6 physicochemical & handling reference →Upstream reference sheetView CPC Scientific catalog page for DEFS-008 →Add to cart · International research catalogBuy alpha-Defensin 6 in the kindr Peptides Shop →

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Research & medical disclosure. This page is educational reference content reviewed by a licensed physician. It is not medical advice and does not establish a clinician–patient relationship. Peptides offered on the kindr Peptides Shop are sold for in vitro laboratory research purposes only and ship internationally — not to the United States. For U.S. clinical care, use the kindr Longevity intake.