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Cardiovascular · Cardiovascular research peptide · ENDT-005

Endothelin-3, human

Research use · ships internationally
$90.00 / 1mg vial
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Endothelin-3, human reference vial
Drug class
Cardiovascular research peptide
Status
Research use only
Catalog code
ENDT-005
Also known as
ENDT-005
Reviewed
2026-06-01 · Kindr Health Clinical Team

What Endothelin-3, human is studied for

  • Vascular reactivity in aortic ring and mesenteric bed preparations
  • Renin–angiotensin–aldosterone system (RAAS) mechanistic studies
  • Natriuretic and diuretic pathway characterization
  • Cardiac remodeling and hypertrophy models

Mechanism of action

Endothelin-3, human sits within the Cardiovascular research class (CPC reference ENDT-005). Cardiovascular peptides act on GPCRs and receptor systems in vascular smooth muscle, endothelium, and cardiac myocytes — modulating vasoconstriction, natriuresis, RAAS signaling, or ionotropic responses. Effects are typically measured in isolated vessel, Langendorff heart, or receptor-transfected cell assays.</ Investigators typically incorporate Endothelin-3, human as a reference standard, tool ligand, or substrate in the assay contexts listed above. Radioligand-binding, IP-1 / cAMP HTRF, and organ-bath tension recordings are the standard readouts.

Frequently asked questions

What is Endothelin-3, human?

Endothelin-3, human (CPC catalog code ENDT-005) is a synthetic cardiovascular research peptide in the cardiovascular category. It is provided as a lyophilized ~1 mg vial for in-vitro research use only.

What is Endothelin-3, human studied for?

Published and internal research programs use Endothelin-3, human as a reference standard in cardiovascular workflows — for example, vascular reactivity in aortic ring and mesenteric bed preparations and renin–angiotensin–aldosterone system (raas) mechanistic studies. Human clinical evidence is not established.

Is Endothelin-3, human FDA-approved for human use?

No. Endothelin-3, human is a research-grade reference peptide and is not approved by the FDA or any national regulator for human or veterinary therapeutic use. It is offered exclusively for in-vitro laboratory research and does not ship to the United States for consumer use.

How is Endothelin-3, human typically used in the lab?

In a cardiovascular workflow, Endothelin-3, human is reconstituted in sterile buffer or DMSO (solubility-dependent) and applied in the researcher's chosen assay format. Radioligand-binding, IP-1 / cAMP HTRF, and organ-bath tension recordings are the standard readouts.

How should Endothelin-3, human be stored?

Stable lyophilized at −20 °C for ≥24 months. Reconstitute in normal saline or PBS. Follow your institution's standard operating procedures for handling synthetic peptides.

Where does the Endothelin-3, human product page point to?

This kindr reference page mirrors CPC Scientific's catalog metadata for ENDT-005. The upstream reference sheet — including sequence, purity, MW, and application notes where published — is linked from the buy panel. All orders placed on kindr Peptides ship internationally under research-use terms only.

What quality specifications apply to Endothelin-3, human?

Research-grade peptides in the CPC catalog are synthesized by solid-phase peptide synthesis (SPPS), purified by preparative RP-HPLC, and characterized by analytical HPLC and mass spectrometry. Typical purity is ≥95%; certificate of analysis is available on request.

Internal reference sheetOpen the Endothelin-3, human physicochemical & handling reference →Upstream reference sheetView CPC Scientific catalog page for ENDT-005 →Add to cart · International research catalogBuy Endothelin-3, human in the kindr Peptides Shop →

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Research & medical disclosure. This page is educational reference content reviewed by a licensed physician. It is not medical advice and does not establish a clinician–patient relationship. Peptides offered on the kindr Peptides Shop are sold for in vitro laboratory research purposes only and ship internationally — not to the United States. For U.S. clinical care, use the kindr Longevity intake.