Opioid · Opioid-receptor research peptide · ENKP-001
DPDPE
- Drug class
- Opioid-receptor research peptide
- Status
- Research use only
- Catalog code
- ENKP-001
- Also known as
- ENKP-001
- Reviewed
- 2026-06-01 · Kindr Health Clinical Team
What DPDPE is studied for
- Opioid-receptor binding and selectivity profiling
- β-arrestin recruitment and biased-agonism studies
- Analgesic mechanism research
- Tolerance and dependence models
Mechanism of action
DPDPE sits within the Opioid research class (CPC reference ENKP-001). Opioid peptides bind μ, δ, and κ receptors — Gi/o-coupled GPCRs that inhibit adenylate cyclase, activate GIRK channels, and modulate calcium currents to produce analgesia, tolerance, and reward-circuit effects. Investigators typically incorporate DPDPE as a reference standard, tool ligand, or substrate in the assay contexts listed above. GTPγS binding, cAMP HTRF, and β-arrestin PathHunter assays.
Frequently asked questions
What is DPDPE?
DPDPE (CPC catalog code ENKP-001) is a synthetic opioid-receptor research peptide in the opioid category. It is provided as a lyophilized ~1 mg vial for in-vitro research use only.
What is DPDPE studied for?
Published and internal research programs use DPDPE as a reference standard in opioid workflows — for example, opioid-receptor binding and selectivity profiling and β-arrestin recruitment and biased-agonism studies. Human clinical evidence is not established.
Is DPDPE FDA-approved for human use?
No. DPDPE is a research-grade reference peptide and is not approved by the FDA or any national regulator for human or veterinary therapeutic use. It is offered exclusively for in-vitro laboratory research and does not ship to the United States for consumer use.
How is DPDPE typically used in the lab?
In a opioid workflow, DPDPE is reconstituted in sterile buffer or DMSO (solubility-dependent) and applied in the researcher's chosen assay format. GTPγS binding, cAMP HTRF, and β-arrestin PathHunter assays.
How should DPDPE be stored?
Store lyophilized at −20 °C. Handle as Schedule research reagents where applicable. Follow your institution's standard operating procedures for handling synthetic peptides.
Where does the DPDPE product page point to?
This kindr reference page mirrors CPC Scientific's catalog metadata for ENKP-001. The upstream reference sheet — including sequence, purity, MW, and application notes where published — is linked from the buy panel. All orders placed on kindr Peptides ship internationally under research-use terms only.
What quality specifications apply to DPDPE?
Research-grade peptides in the CPC catalog are synthesized by solid-phase peptide synthesis (SPPS), purified by preparative RP-HPLC, and characterized by analytical HPLC and mass spectrometry. Typical purity is ≥95%; certificate of analysis is available on request.
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