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Histone / Epigenetic · Histone / epigenetic reader-writer substrate · HIST-006

Ac-RGK(Ac)-AMC

Research use · ships internationally
$90.00 / 1mg vial
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Ac-RGK(Ac)-AMC reference vial
Drug class
Histone / epigenetic reader-writer substrate
Status
Research use only
Catalog code
HIST-006
Also known as
HIST-006
Reviewed
2026-06-01 · Kindr Health Clinical Team

What Ac-RGK(Ac)-AMC is studied for

  • HAT / HDAC / HMT / KDM activity assays
  • Bromodomain and chromodomain binding studies
  • Epigenetic inhibitor screening
  • Chromatin-mark specificity profiling

Mechanism of action

Ac-RGK(Ac)-AMC sits within the Histone / Epigenetic research class (CPC reference HIST-006). These peptides carry defined post-translational modifications (methylation, acetylation, phosphorylation) at N-terminal histone tail residues, allowing biochemical characterization of writers (HMTs, HATs), erasers (KDMs, HDACs), and readers (bromodomains, chromodomains). Investigators typically incorporate Ac-RGK(Ac)-AMC as a reference standard, tool ligand, or substrate in the assay contexts listed above. SPR / BLI binding, AlphaScreen, TR-FRET, and MS-based activity assays.

Frequently asked questions

What is Ac-RGK(Ac)-AMC?

Ac-RGK(Ac)-AMC (CPC catalog code HIST-006) is a synthetic histone / epigenetic reader-writer substrate in the histone / epigenetic category. It is provided as a lyophilized ~1 mg vial for in-vitro research use only.

What is Ac-RGK(Ac)-AMC studied for?

Published and internal research programs use Ac-RGK(Ac)-AMC as a reference standard in histone / epigenetic workflows — for example, hat / hdac / hmt / kdm activity assays and bromodomain and chromodomain binding studies. Human clinical evidence is not established.

Is Ac-RGK(Ac)-AMC FDA-approved for human use?

No. Ac-RGK(Ac)-AMC is a research-grade reference peptide and is not approved by the FDA or any national regulator for human or veterinary therapeutic use. It is offered exclusively for in-vitro laboratory research and does not ship to the United States for consumer use.

How is Ac-RGK(Ac)-AMC typically used in the lab?

In a histone / epigenetic workflow, Ac-RGK(Ac)-AMC is reconstituted in sterile buffer or DMSO (solubility-dependent) and applied in the researcher's chosen assay format. SPR / BLI binding, AlphaScreen, TR-FRET, and MS-based activity assays.

How should Ac-RGK(Ac)-AMC be stored?

Store lyophilized at −20 °C. Reconstitute in low-salt buffer; avoid repeated freeze–thaw. Follow your institution's standard operating procedures for handling synthetic peptides.

Where does the Ac-RGK(Ac)-AMC product page point to?

This kindr reference page mirrors CPC Scientific's catalog metadata for HIST-006. The upstream reference sheet — including sequence, purity, MW, and application notes where published — is linked from the buy panel. All orders placed on kindr Peptides ship internationally under research-use terms only.

What quality specifications apply to Ac-RGK(Ac)-AMC?

Research-grade peptides in the CPC catalog are synthesized by solid-phase peptide synthesis (SPPS), purified by preparative RP-HPLC, and characterized by analytical HPLC and mass spectrometry. Typical purity is ≥95%; certificate of analysis is available on request.

Internal reference sheetOpen the Ac-RGK(Ac)-AMC physicochemical & handling reference →Upstream reference sheetView CPC Scientific catalog page for HIST-006 →Add to cart · International research catalogBuy Ac-RGK(Ac)-AMC in the kindr Peptides Shop →

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Research & medical disclosure. This page is educational reference content reviewed by a licensed physician. It is not medical advice and does not establish a clinician–patient relationship. Peptides offered on the kindr Peptides Shop are sold for in vitro laboratory research purposes only and ship internationally — not to the United States. For U.S. clinical care, use the kindr Longevity intake.