[Lys(Me3)27]-Histone H3 (21-44), biotin-labeled

[Lys(Me3)27]-Histone H3 (21-44), biotin-labeled (CPC catalog code HIST-058) is a synthetic histone / epigenetic reader-writer substrate in the histone / epigenetic category. It is provided as a lyophilized ~1 mg vial for in-vitro research use only.

Published and internal research programs use [Lys(Me3)27]-Histone H3 (21-44), biotin-labeled as a reference standard in histone / epigenetic workflows — for example, hat / hdac / hmt / kdm activity assays and bromodomain and chromodomain binding studies. Human clinical evidence is not established.

No. [Lys(Me3)27]-Histone H3 (21-44), biotin-labeled is a research-grade reference peptide and is not approved by the FDA or any national regulator for human or veterinary therapeutic use. It is offered exclusively for in-vitro laboratory research and does not ship to the United States for consumer use.

In a histone / epigenetic workflow, [Lys(Me3)27]-Histone H3 (21-44), biotin-labeled is reconstituted in sterile buffer or DMSO (solubility-dependent) and applied in the researcher's chosen assay format. SPR / BLI binding, AlphaScreen, TR-FRET, and MS-based activity assays.

Store lyophilized at −20 °C. Reconstitute in low-salt buffer; avoid repeated freeze–thaw. Follow your institution's standard operating procedures for handling synthetic peptides.

This kindr reference page mirrors CPC Scientific's catalog metadata for HIST-058. The upstream reference sheet — including sequence, purity, MW, and application notes where published — is linked from the buy panel. All orders placed on kindr Peptides ship internationally under research-use terms only.

Research-grade peptides in the CPC catalog are synthesized by solid-phase peptide synthesis (SPPS), purified by preparative RP-HPLC, and characterized by analytical HPLC and mass spectrometry. Typical purity is ≥95%; certificate of analysis is available on request.