Antimicrobial · Antimicrobial peptide (AMP) reference standard · LL37-004
Biotinyl-LL-37 amide
- Drug class
- Antimicrobial peptide (AMP) reference standard
- Status
- Research use only
- Catalog code
- LL37-004
- Also known as
- LL37-004
- Reviewed
- 2026-06-01 · Kindr Health Clinical Team
What Biotinyl-LL-37 amide is studied for
- Minimum inhibitory concentration (MIC) screens against Gram-positive and Gram-negative panels
- Biofilm disruption and anti-biofilm surface coatings
- Structure–activity relationship (SAR) studies for AMP analogues
- Host-defense and innate-immunity mechanistic work
Mechanism of action
Biotinyl-LL-37 amide sits within the Antimicrobial research class (CPC reference LL37-004). Antimicrobial peptides typically disrupt bacterial, fungal, or viral membranes through direct electrostatic and hydrophobic interactions, or by triggering intracellular targets after translocation. Assay potency is usually reported as MIC (minimum inhibitory concentration) against reference strains. Investigators typically incorporate Biotinyl-LL-37 amide as a reference standard, tool ligand, or substrate in the assay contexts listed above. Most commonly used in broth microdilution MIC assays (CLSI M07), radial diffusion assays, and membrane-permeabilization (SYTOX / DiSC₃-5) readouts.
Frequently asked questions
What is Biotinyl-LL-37 amide?
Biotinyl-LL-37 amide (CPC catalog code LL37-004) is a synthetic antimicrobial peptide (amp) reference standard in the antimicrobial category. It is provided as a lyophilized ~1 mg vial for in-vitro research use only.
What is Biotinyl-LL-37 amide studied for?
Published and internal research programs use Biotinyl-LL-37 amide as a reference standard in antimicrobial workflows — for example, minimum inhibitory concentration (mic) screens against gram-positive and gram-negative panels and biofilm disruption and anti-biofilm surface coatings. Human clinical evidence is not established.
Is Biotinyl-LL-37 amide FDA-approved for human use?
No. Biotinyl-LL-37 amide is a research-grade reference peptide and is not approved by the FDA or any national regulator for human or veterinary therapeutic use. It is offered exclusively for in-vitro laboratory research and does not ship to the United States for consumer use.
How is Biotinyl-LL-37 amide typically used in the lab?
In a antimicrobial workflow, Biotinyl-LL-37 amide is reconstituted in sterile buffer or DMSO (solubility-dependent) and applied in the researcher's chosen assay format. Most commonly used in broth microdilution MIC assays (CLSI M07), radial diffusion assays, and membrane-permeabilization (SYTOX / DiSC₃-5) readouts.
How should Biotinyl-LL-37 amide be stored?
Lyophilized peptide is stable long-term at −20 °C. Reconstituted stock solutions are typically stored at 4 °C for short-term use or aliquoted and frozen for longer storage. Follow your institution's standard operating procedures for handling synthetic peptides.
Where does the Biotinyl-LL-37 amide product page point to?
This kindr reference page mirrors CPC Scientific's catalog metadata for LL37-004. The upstream reference sheet — including sequence, purity, MW, and application notes where published — is linked from the buy panel. All orders placed on kindr Peptides ship internationally under research-use terms only.
What quality specifications apply to Biotinyl-LL-37 amide?
Research-grade peptides in the CPC catalog are synthesized by solid-phase peptide synthesis (SPPS), purified by preparative RP-HPLC, and characterized by analytical HPLC and mass spectrometry. Typical purity is ≥95%; certificate of analysis is available on request.
Related peptides in Antimicrobial
Continue across the Kindr entity graph
Related evidence, peptides, and clinical tools on the same topic.
