Protease Substrates · Protease substrate (research reagent) · MMPS-027
Thrombin Substrate III, Fluorogenic
- Drug class
- Protease substrate (research reagent)
- Status
- Research use only
- Catalog code
- MMPS-027
- Also known as
- MMPS-027
- Reviewed
- 2026-06-01 · Kindr Health Clinical Team
What Thrombin Substrate III, Fluorogenic is studied for
- Kinetic (kcat / Km) protease characterization
- Inhibitor screening and IC₅₀ determination
- Selectivity profiling across protease families
- Cell-based and diagnostic activity assays
Mechanism of action
Thrombin Substrate III, Fluorogenic sits within the Protease Substrates research class (CPC reference MMPS-027). The peptide encodes a specific protease-recognition motif flanked by a reporter (pNA, AMC, MCA / Dnp FRET pair). Enzymatic cleavage releases the reporter, producing signal directly proportional to catalytic activity. Investigators typically incorporate Thrombin Substrate III, Fluorogenic as a reference standard, tool ligand, or substrate in the assay contexts listed above. Read on kinetic plate readers at the reporter-appropriate wavelength.
Frequently asked questions
What is Thrombin Substrate III, Fluorogenic?
Thrombin Substrate III, Fluorogenic (CPC catalog code MMPS-027) is a synthetic protease substrate (research reagent) in the protease substrates category. It is provided as a lyophilized ~1 mg vial for in-vitro research use only.
What is Thrombin Substrate III, Fluorogenic studied for?
Published and internal research programs use Thrombin Substrate III, Fluorogenic as a reference standard in protease substrates workflows — for example, kinetic (kcat / km) protease characterization and inhibitor screening and ic₅₀ determination. Human clinical evidence is not established.
Is Thrombin Substrate III, Fluorogenic FDA-approved for human use?
No. Thrombin Substrate III, Fluorogenic is a research-grade reference peptide and is not approved by the FDA or any national regulator for human or veterinary therapeutic use. It is offered exclusively for in-vitro laboratory research and does not ship to the United States for consumer use.
How is Thrombin Substrate III, Fluorogenic typically used in the lab?
In a protease substrates workflow, Thrombin Substrate III, Fluorogenic is reconstituted in sterile buffer or DMSO (solubility-dependent) and applied in the researcher's chosen assay format. Read on kinetic plate readers at the reporter-appropriate wavelength.
How should Thrombin Substrate III, Fluorogenic be stored?
Store lyophilized at −20 °C, protected from light. DMSO stocks stable at −80 °C. Follow your institution's standard operating procedures for handling synthetic peptides.
Where does the Thrombin Substrate III, Fluorogenic product page point to?
This kindr reference page mirrors CPC Scientific's catalog metadata for MMPS-027. The upstream reference sheet — including sequence, purity, MW, and application notes where published — is linked from the buy panel. All orders placed on kindr Peptides ship internationally under research-use terms only.
What quality specifications apply to Thrombin Substrate III, Fluorogenic?
Research-grade peptides in the CPC catalog are synthesized by solid-phase peptide synthesis (SPPS), purified by preparative RP-HPLC, and characterized by analytical HPLC and mass spectrometry. Typical purity is ≥95%; certificate of analysis is available on request.
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