Neuropeptides · Neuropeptide receptor ligand · NEUP-004
GR 83074
- Drug class
- Neuropeptide receptor ligand
- Status
- Research use only
- Catalog code
- NEUP-004
- Also known as
- NEUP-004
- Reviewed
- 2026-06-01 · Kindr Health Clinical Team
What GR 83074 is studied for
- GPCR receptor-binding and functional profiling
- Behavioral pharmacology (rodent models)
- Pain, mood, and anxiety-circuit research
- Neuroendocrine feedback studies
Mechanism of action
GR 83074 sits within the Neuropeptides research class (CPC reference NEUP-004). Neuropeptides bind GPCRs expressed on central and peripheral neurons — modulating cAMP, calcium, and β-arrestin signaling to shape neurotransmission, network excitability, and behavior. Investigators typically incorporate GR 83074 as a reference standard, tool ligand, or substrate in the assay contexts listed above. Radioligand binding, cAMP HTRF, calcium mobilization, and in vivo behavior assays.
Frequently asked questions
What is GR 83074?
GR 83074 (CPC catalog code NEUP-004) is a synthetic neuropeptide receptor ligand in the neuropeptides category. It is provided as a lyophilized ~1 mg vial for in-vitro research use only.
What is GR 83074 studied for?
Published and internal research programs use GR 83074 as a reference standard in neuropeptides workflows — for example, gpcr receptor-binding and functional profiling and behavioral pharmacology (rodent models). Human clinical evidence is not established.
Is GR 83074 FDA-approved for human use?
No. GR 83074 is a research-grade reference peptide and is not approved by the FDA or any national regulator for human or veterinary therapeutic use. It is offered exclusively for in-vitro laboratory research and does not ship to the United States for consumer use.
How is GR 83074 typically used in the lab?
In a neuropeptides workflow, GR 83074 is reconstituted in sterile buffer or DMSO (solubility-dependent) and applied in the researcher's chosen assay format. Radioligand binding, cAMP HTRF, calcium mobilization, and in vivo behavior assays.
How should GR 83074 be stored?
Store lyophilized at −20 °C. Reconstitute in sterile 0.1% BSA/PBS to reduce adsorption. Follow your institution's standard operating procedures for handling synthetic peptides.
Where does the GR 83074 product page point to?
This kindr reference page mirrors CPC Scientific's catalog metadata for NEUP-004. The upstream reference sheet — including sequence, purity, MW, and application notes where published — is linked from the buy panel. All orders placed on kindr Peptides ship internationally under research-use terms only.
What quality specifications apply to GR 83074?
Research-grade peptides in the CPC catalog are synthesized by solid-phase peptide synthesis (SPPS), purified by preparative RP-HPLC, and characterized by analytical HPLC and mass spectrometry. Typical purity is ≥95%; certificate of analysis is available on request.
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