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Opioid · Opioid-receptor research peptide · OPIO-003

Dermorphin

Research use · ships internationally
$85.00 / 1mg vial
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Dermorphin reference vial
Drug class
Opioid-receptor research peptide
Status
Research use only
Catalog code
OPIO-003
Also known as
OPIO-003
Reviewed
2026-06-01 · Kindr Health Clinical Team

What Dermorphin is studied for

  • Opioid-receptor binding and selectivity profiling
  • β-arrestin recruitment and biased-agonism studies
  • Analgesic mechanism research
  • Tolerance and dependence models

Mechanism of action

Dermorphin sits within the Opioid research class (CPC reference OPIO-003). Opioid peptides bind μ, δ, and κ receptors — Gi/o-coupled GPCRs that inhibit adenylate cyclase, activate GIRK channels, and modulate calcium currents to produce analgesia, tolerance, and reward-circuit effects. Investigators typically incorporate Dermorphin as a reference standard, tool ligand, or substrate in the assay contexts listed above. GTPγS binding, cAMP HTRF, and β-arrestin PathHunter assays.

Frequently asked questions

What is Dermorphin?

Dermorphin (CPC catalog code OPIO-003) is a synthetic opioid-receptor research peptide in the opioid category. It is provided as a lyophilized ~1 mg vial for in-vitro research use only.

What is Dermorphin studied for?

Published and internal research programs use Dermorphin as a reference standard in opioid workflows — for example, opioid-receptor binding and selectivity profiling and β-arrestin recruitment and biased-agonism studies. Human clinical evidence is not established.

Is Dermorphin FDA-approved for human use?

No. Dermorphin is a research-grade reference peptide and is not approved by the FDA or any national regulator for human or veterinary therapeutic use. It is offered exclusively for in-vitro laboratory research and does not ship to the United States for consumer use.

How is Dermorphin typically used in the lab?

In a opioid workflow, Dermorphin is reconstituted in sterile buffer or DMSO (solubility-dependent) and applied in the researcher's chosen assay format. GTPγS binding, cAMP HTRF, and β-arrestin PathHunter assays.

How should Dermorphin be stored?

Store lyophilized at −20 °C. Handle as Schedule research reagents where applicable. Follow your institution's standard operating procedures for handling synthetic peptides.

Where does the Dermorphin product page point to?

This kindr reference page mirrors CPC Scientific's catalog metadata for OPIO-003. The upstream reference sheet — including sequence, purity, MW, and application notes where published — is linked from the buy panel. All orders placed on kindr Peptides ship internationally under research-use terms only.

What quality specifications apply to Dermorphin?

Research-grade peptides in the CPC catalog are synthesized by solid-phase peptide synthesis (SPPS), purified by preparative RP-HPLC, and characterized by analytical HPLC and mass spectrometry. Typical purity is ≥95%; certificate of analysis is available on request.

Internal reference sheetOpen the Dermorphin physicochemical & handling reference →Upstream reference sheetView CPC Scientific catalog page for OPIO-003 →Add to cart · International research catalogBuy Dermorphin in the kindr Peptides Shop →

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[DArg2,Lys4]-Dermorphin (1-4), amideResearch-grade opioid · CPC OPIO-004
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DeltorphinResearch-grade opioid · CPC OPIO-010
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Research & medical disclosure. This page is educational reference content reviewed by a licensed physician. It is not medical advice and does not establish a clinician–patient relationship. Peptides offered on the kindr Peptides Shop are sold for in vitro laboratory research purposes only and ship internationally — not to the United States. For U.S. clinical care, use the kindr Longevity intake.