Endocrine · Endocrine research peptide · PACA-008
PACAP-38 (6-38) (human, chicken, mouse, ovine, porcine, rat)
- Drug class
- Endocrine research peptide
- Status
- Research use only
- Catalog code
- PACA-008
- Also known as
- PACA-008
- Reviewed
- 2026-06-01 · Kindr Health Clinical Team
What PACAP-38 (6-38) (human, chicken, mouse, ovine, porcine, rat) is studied for
- Receptor-binding and functional selectivity studies
- Second-messenger (cAMP / IP₁) profiling
- Hypothalamic–pituitary axis feedback modeling
- Metabolic and glucose-homeostasis research
Mechanism of action
PACAP-38 (6-38) (human, chicken, mouse, ovine, porcine, rat) sits within the Endocrine research class (CPC reference PACA-008). Endocrine peptides bind class A/B GPCRs and RTKs on hormone-responsive tissues, triggering canonical cAMP, IP₃/Ca²⁺, and MAPK pathways that regulate secretion, growth, and metabolism. Investigators typically incorporate PACAP-38 (6-38) (human, chicken, mouse, ovine, porcine, rat) as a reference standard, tool ligand, or substrate in the assay contexts listed above. HTRF cAMP, calcium mobilization (FLIPR), and radioligand binding are the standard readouts.
Frequently asked questions
What is PACAP-38 (6-38) (human, chicken, mouse, ovine, porcine, rat)?
PACAP-38 (6-38) (human, chicken, mouse, ovine, porcine, rat) (CPC catalog code PACA-008) is a synthetic endocrine research peptide in the endocrine category. It is provided as a lyophilized ~1 mg vial for in-vitro research use only.
What is PACAP-38 (6-38) (human, chicken, mouse, ovine, porcine, rat) studied for?
Published and internal research programs use PACAP-38 (6-38) (human, chicken, mouse, ovine, porcine, rat) as a reference standard in endocrine workflows — for example, receptor-binding and functional selectivity studies and second-messenger (camp / ip₁) profiling. Human clinical evidence is not established.
Is PACAP-38 (6-38) (human, chicken, mouse, ovine, porcine, rat) FDA-approved for human use?
No. PACAP-38 (6-38) (human, chicken, mouse, ovine, porcine, rat) is a research-grade reference peptide and is not approved by the FDA or any national regulator for human or veterinary therapeutic use. It is offered exclusively for in-vitro laboratory research and does not ship to the United States for consumer use.
How is PACAP-38 (6-38) (human, chicken, mouse, ovine, porcine, rat) typically used in the lab?
In a endocrine workflow, PACAP-38 (6-38) (human, chicken, mouse, ovine, porcine, rat) is reconstituted in sterile buffer or DMSO (solubility-dependent) and applied in the researcher's chosen assay format. HTRF cAMP, calcium mobilization (FLIPR), and radioligand binding are the standard readouts.
How should PACAP-38 (6-38) (human, chicken, mouse, ovine, porcine, rat) be stored?
Store lyophilized at −20 °C, protected from light. Reconstitute in sterile 0.1% BSA/PBS. Follow your institution's standard operating procedures for handling synthetic peptides.
Where does the PACAP-38 (6-38) (human, chicken, mouse, ovine, porcine, rat) product page point to?
This kindr reference page mirrors CPC Scientific's catalog metadata for PACA-008. The upstream reference sheet — including sequence, purity, MW, and application notes where published — is linked from the buy panel. All orders placed on kindr Peptides ship internationally under research-use terms only.
What quality specifications apply to PACAP-38 (6-38) (human, chicken, mouse, ovine, porcine, rat)?
Research-grade peptides in the CPC catalog are synthesized by solid-phase peptide synthesis (SPPS), purified by preparative RP-HPLC, and characterized by analytical HPLC and mass spectrometry. Typical purity is ≥95%; certificate of analysis is available on request.
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