Protease Substrates · Protease substrate (research reagent) · RENI-014
Renin Inhibitor III
- Drug class
- Protease substrate (research reagent)
- Status
- Research use only
- Catalog code
- RENI-014
- Also known as
- RENI-014
- Reviewed
- 2026-06-01 · Kindr Health Clinical Team
What Renin Inhibitor III is studied for
- Kinetic (kcat / Km) protease characterization
- Inhibitor screening and IC₅₀ determination
- Selectivity profiling across protease families
- Cell-based and diagnostic activity assays
Mechanism of action
Renin Inhibitor III sits within the Protease Substrates research class (CPC reference RENI-014). The peptide encodes a specific protease-recognition motif flanked by a reporter (pNA, AMC, MCA / Dnp FRET pair). Enzymatic cleavage releases the reporter, producing signal directly proportional to catalytic activity. Investigators typically incorporate Renin Inhibitor III as a reference standard, tool ligand, or substrate in the assay contexts listed above. Read on kinetic plate readers at the reporter-appropriate wavelength.
Frequently asked questions
What is Renin Inhibitor III?
Renin Inhibitor III (CPC catalog code RENI-014) is a synthetic protease substrate (research reagent) in the protease substrates category. It is provided as a lyophilized ~1 mg vial for in-vitro research use only.
What is Renin Inhibitor III studied for?
Published and internal research programs use Renin Inhibitor III as a reference standard in protease substrates workflows — for example, kinetic (kcat / km) protease characterization and inhibitor screening and ic₅₀ determination. Human clinical evidence is not established.
Is Renin Inhibitor III FDA-approved for human use?
No. Renin Inhibitor III is a research-grade reference peptide and is not approved by the FDA or any national regulator for human or veterinary therapeutic use. It is offered exclusively for in-vitro laboratory research and does not ship to the United States for consumer use.
How is Renin Inhibitor III typically used in the lab?
In a protease substrates workflow, Renin Inhibitor III is reconstituted in sterile buffer or DMSO (solubility-dependent) and applied in the researcher's chosen assay format. Read on kinetic plate readers at the reporter-appropriate wavelength.
How should Renin Inhibitor III be stored?
Store lyophilized at −20 °C, protected from light. DMSO stocks stable at −80 °C. Follow your institution's standard operating procedures for handling synthetic peptides.
Where does the Renin Inhibitor III product page point to?
This kindr reference page mirrors CPC Scientific's catalog metadata for RENI-014. The upstream reference sheet — including sequence, purity, MW, and application notes where published — is linked from the buy panel. All orders placed on kindr Peptides ship internationally under research-use terms only.
What quality specifications apply to Renin Inhibitor III?
Research-grade peptides in the CPC catalog are synthesized by solid-phase peptide synthesis (SPPS), purified by preparative RP-HPLC, and characterized by analytical HPLC and mass spectrometry. Typical purity is ≥95%; certificate of analysis is available on request.
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