Signaling · Cell-signaling research peptide · SIGN-012
PDE(p), Calmodulin Binding Domain
- Drug class
- Cell-signaling research peptide
- Status
- Research use only
- Catalog code
- SIGN-012
- Also known as
- SIGN-012
- Reviewed
- 2026-06-01 · Kindr Health Clinical Team
What PDE(p), Calmodulin Binding Domain is studied for
- Protein–protein interaction (PPI) mapping
- SH2, SH3, PDZ, and 14-3-3 binding studies
- Allosteric modulator and PPI-inhibitor discovery
- Signal-pathway dissection in cellular models
Mechanism of action
PDE(p), Calmodulin Binding Domain sits within the Signaling research class (CPC reference SIGN-012). Signaling peptides mimic recognition motifs (phosphotyrosine motifs, PDZ ligands, kinase docking sites) or interfere with protein–protein interactions inside the cell, allowing focused perturbation of a single node in a pathway. Investigators typically incorporate PDE(p), Calmodulin Binding Domain as a reference standard, tool ligand, or substrate in the assay contexts listed above. SPR, BLI, AlphaScreen, and pulldown / Western readouts.
Frequently asked questions
What is PDE(p), Calmodulin Binding Domain?
PDE(p), Calmodulin Binding Domain (CPC catalog code SIGN-012) is a synthetic cell-signaling research peptide in the signaling category. It is provided as a lyophilized ~1 mg vial for in-vitro research use only.
What is PDE(p), Calmodulin Binding Domain studied for?
Published and internal research programs use PDE(p), Calmodulin Binding Domain as a reference standard in signaling workflows — for example, protein–protein interaction (ppi) mapping and sh2, sh3, pdz, and 14-3-3 binding studies. Human clinical evidence is not established.
Is PDE(p), Calmodulin Binding Domain FDA-approved for human use?
No. PDE(p), Calmodulin Binding Domain is a research-grade reference peptide and is not approved by the FDA or any national regulator for human or veterinary therapeutic use. It is offered exclusively for in-vitro laboratory research and does not ship to the United States for consumer use.
How is PDE(p), Calmodulin Binding Domain typically used in the lab?
In a signaling workflow, PDE(p), Calmodulin Binding Domain is reconstituted in sterile buffer or DMSO (solubility-dependent) and applied in the researcher's chosen assay format. SPR, BLI, AlphaScreen, and pulldown / Western readouts.
How should PDE(p), Calmodulin Binding Domain be stored?
Store lyophilized at −20 °C. Aliquot in DMSO or aqueous buffer per solubility. Follow your institution's standard operating procedures for handling synthetic peptides.
Where does the PDE(p), Calmodulin Binding Domain product page point to?
This kindr reference page mirrors CPC Scientific's catalog metadata for SIGN-012. The upstream reference sheet — including sequence, purity, MW, and application notes where published — is linked from the buy panel. All orders placed on kindr Peptides ship internationally under research-use terms only.
What quality specifications apply to PDE(p), Calmodulin Binding Domain?
Research-grade peptides in the CPC catalog are synthesized by solid-phase peptide synthesis (SPPS), purified by preparative RP-HPLC, and characterized by analytical HPLC and mass spectrometry. Typical purity is ≥95%; certificate of analysis is available on request.
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