GI / Gut · Gastrointestinal / gut-hormone peptide · SUBP-001
[DArg1,DPhe5,DTrp7,9,Leu11] Substance P
- Drug class
- Gastrointestinal / gut-hormone peptide
- Status
- Research use only
- Catalog code
- SUBP-001
- Also known as
- SUBP-001
- Reviewed
- 2026-06-01 · Kindr Health Clinical Team
What [DArg1,DPhe5,DTrp7,9,Leu11] Substance P is studied for
- Incretin (GLP-1 / GIP) receptor signaling
- Appetite and satiety-circuit research
- Gastric motility and emptying assays
- Gut–brain axis and vagal signaling models
Mechanism of action
[DArg1,DPhe5,DTrp7,9,Leu11] Substance P sits within the GI / Gut research class (CPC reference SUBP-001). Gut peptides engage GPCRs on enteroendocrine cells, vagal afferents, and central nuclei, modulating motility, secretion, satiety, and glucose-dependent insulin release. Investigators typically incorporate [DArg1,DPhe5,DTrp7,9,Leu11] Substance P as a reference standard, tool ligand, or substrate in the assay contexts listed above. cAMP HTRF, in vitro islet insulin secretion, and food-intake models in rodents.
Frequently asked questions
What is [DArg1,DPhe5,DTrp7,9,Leu11] Substance P?
[DArg1,DPhe5,DTrp7,9,Leu11] Substance P (CPC catalog code SUBP-001) is a synthetic gastrointestinal / gut-hormone peptide in the gi / gut category. It is provided as a lyophilized ~1 mg vial for in-vitro research use only.
What is [DArg1,DPhe5,DTrp7,9,Leu11] Substance P studied for?
Published and internal research programs use [DArg1,DPhe5,DTrp7,9,Leu11] Substance P as a reference standard in gi / gut workflows — for example, incretin (glp-1 / gip) receptor signaling and appetite and satiety-circuit research. Human clinical evidence is not established.
Is [DArg1,DPhe5,DTrp7,9,Leu11] Substance P FDA-approved for human use?
No. [DArg1,DPhe5,DTrp7,9,Leu11] Substance P is a research-grade reference peptide and is not approved by the FDA or any national regulator for human or veterinary therapeutic use. It is offered exclusively for in-vitro laboratory research and does not ship to the United States for consumer use.
How is [DArg1,DPhe5,DTrp7,9,Leu11] Substance P typically used in the lab?
In a gi / gut workflow, [DArg1,DPhe5,DTrp7,9,Leu11] Substance P is reconstituted in sterile buffer or DMSO (solubility-dependent) and applied in the researcher's chosen assay format. cAMP HTRF, in vitro islet insulin secretion, and food-intake models in rodents.
How should [DArg1,DPhe5,DTrp7,9,Leu11] Substance P be stored?
Store lyophilized at −20 °C. Reconstitute in acidified water (0.1% acetic acid) for stability. Follow your institution's standard operating procedures for handling synthetic peptides.
Where does the [DArg1,DPhe5,DTrp7,9,Leu11] Substance P product page point to?
This kindr reference page mirrors CPC Scientific's catalog metadata for SUBP-001. The upstream reference sheet — including sequence, purity, MW, and application notes where published — is linked from the buy panel. All orders placed on kindr Peptides ship internationally under research-use terms only.
What quality specifications apply to [DArg1,DPhe5,DTrp7,9,Leu11] Substance P?
Research-grade peptides in the CPC catalog are synthesized by solid-phase peptide synthesis (SPPS), purified by preparative RP-HPLC, and characterized by analytical HPLC and mass spectrometry. Typical purity is ≥95%; certificate of analysis is available on request.
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![[DArg1,DPhe5,DTrp7,9,Leu11] Substance P reference vial](/__l5e/assets-v1/83f67069-c2c2-4c3c-94fb-4667a75f74ae/peptide-vial-placeholder.jpg)