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GI / Gut · Gastrointestinal / gut-hormone peptide · SUBP-001

[DArg1,DPhe5,DTrp7,9,Leu11] Substance P

Research use · ships internationally
$85.00 / 1mg vial
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[DArg1,DPhe5,DTrp7,9,Leu11] Substance P reference vial
Drug class
Gastrointestinal / gut-hormone peptide
Status
Research use only
Catalog code
SUBP-001
Also known as
SUBP-001
Reviewed
2026-06-01 · Kindr Health Clinical Team

What [DArg1,DPhe5,DTrp7,9,Leu11] Substance P is studied for

  • Incretin (GLP-1 / GIP) receptor signaling
  • Appetite and satiety-circuit research
  • Gastric motility and emptying assays
  • Gut–brain axis and vagal signaling models

Mechanism of action

[DArg1,DPhe5,DTrp7,9,Leu11] Substance P sits within the GI / Gut research class (CPC reference SUBP-001). Gut peptides engage GPCRs on enteroendocrine cells, vagal afferents, and central nuclei, modulating motility, secretion, satiety, and glucose-dependent insulin release. Investigators typically incorporate [DArg1,DPhe5,DTrp7,9,Leu11] Substance P as a reference standard, tool ligand, or substrate in the assay contexts listed above. cAMP HTRF, in vitro islet insulin secretion, and food-intake models in rodents.

Frequently asked questions

What is [DArg1,DPhe5,DTrp7,9,Leu11] Substance P?

[DArg1,DPhe5,DTrp7,9,Leu11] Substance P (CPC catalog code SUBP-001) is a synthetic gastrointestinal / gut-hormone peptide in the gi / gut category. It is provided as a lyophilized ~1 mg vial for in-vitro research use only.

What is [DArg1,DPhe5,DTrp7,9,Leu11] Substance P studied for?

Published and internal research programs use [DArg1,DPhe5,DTrp7,9,Leu11] Substance P as a reference standard in gi / gut workflows — for example, incretin (glp-1 / gip) receptor signaling and appetite and satiety-circuit research. Human clinical evidence is not established.

Is [DArg1,DPhe5,DTrp7,9,Leu11] Substance P FDA-approved for human use?

No. [DArg1,DPhe5,DTrp7,9,Leu11] Substance P is a research-grade reference peptide and is not approved by the FDA or any national regulator for human or veterinary therapeutic use. It is offered exclusively for in-vitro laboratory research and does not ship to the United States for consumer use.

How is [DArg1,DPhe5,DTrp7,9,Leu11] Substance P typically used in the lab?

In a gi / gut workflow, [DArg1,DPhe5,DTrp7,9,Leu11] Substance P is reconstituted in sterile buffer or DMSO (solubility-dependent) and applied in the researcher's chosen assay format. cAMP HTRF, in vitro islet insulin secretion, and food-intake models in rodents.

How should [DArg1,DPhe5,DTrp7,9,Leu11] Substance P be stored?

Store lyophilized at −20 °C. Reconstitute in acidified water (0.1% acetic acid) for stability. Follow your institution's standard operating procedures for handling synthetic peptides.

Where does the [DArg1,DPhe5,DTrp7,9,Leu11] Substance P product page point to?

This kindr reference page mirrors CPC Scientific's catalog metadata for SUBP-001. The upstream reference sheet — including sequence, purity, MW, and application notes where published — is linked from the buy panel. All orders placed on kindr Peptides ship internationally under research-use terms only.

What quality specifications apply to [DArg1,DPhe5,DTrp7,9,Leu11] Substance P?

Research-grade peptides in the CPC catalog are synthesized by solid-phase peptide synthesis (SPPS), purified by preparative RP-HPLC, and characterized by analytical HPLC and mass spectrometry. Typical purity is ≥95%; certificate of analysis is available on request.

Internal reference sheetOpen the [DArg1,DPhe5,DTrp7,9,Leu11] Substance P physicochemical & handling reference →Upstream reference sheetView CPC Scientific catalog page for SUBP-001 →Add to cart · International research catalogBuy [DArg1,DPhe5,DTrp7,9,Leu11] Substance P in the kindr Peptides Shop →

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Research & medical disclosure. This page is educational reference content reviewed by a licensed physician. It is not medical advice and does not establish a clinician–patient relationship. Peptides offered on the kindr Peptides Shop are sold for in vitro laboratory research purposes only and ship internationally — not to the United States. For U.S. clinical care, use the kindr Longevity intake.