Recovery & Repair · Thymosin beta-4 fragment (research)
TB-500 (Thymosin Beta-4)
- Drug class
- Thymosin beta-4 fragment (research)
- Status
- Compounded (503A)
- Also known as
- Thymosin beta-4, Tβ4, TMSB4X
- Reviewed
- 2026-06-01 · Kindr Health Clinical Team
What TB-500 (Thymosin Beta-4) is studied for
- Soft-tissue and tendon repair (preclinical)
- Cardiac tissue regeneration research
- Wound healing and corneal repair
- Flexibility and muscle recovery
Mechanism of action
Thymosin beta-4 sequesters G-actin, regulating cell migration, angiogenesis, and stem-cell recruitment to injury sites. The TB-500 fragment is a long-acting analog used in animal research.
Frequently asked questions
Is TB-500 the same as thymosin beta-4?
TB-500 is a synthetic fragment of the same active region; full-length thymosin beta-4 (RGN-352) has been studied in human cardiac trials. They are commonly used interchangeably in research.
Why is it banned in equine sport?
WADA and most horse-racing authorities ban TB-500 because of its performance-enhancement and healing potential, even though human clinical evidence is preliminary.
How is it dosed in research?
Subcutaneous injection; protocols vary widely. No validated human therapeutic dose exists.
Is it safe?
Short-term tolerability appears good in animals; long-term human safety is unknown. Theoretical risks include angiogenic effects with cancer history.
Build the TB-500 (Thymosin Beta-4) protocol stack
Research protocols commonly pair TB-500 (Thymosin Beta-4) with the peptides below. Add all three vials to unlock the bundle discount at checkout.
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