We value your privacy

We use cookies to analyze site usage and improve your experience. You can accept all, reject non-essential, or customize. See our Privacy Policy.

kindr currently serves patients in the United States only. Content is for informational purposes elsewhere.

Coagulation · Coagulation cascade peptide / substrate · THRO-022

Thrombin substrate

Research use · ships internationally
$95.00 / 1mg vial
Buy Thrombin substrate →Browse all peptides
Bulk order for a lab or clinic? See wholesale pricing →
Thrombin substrate reference vial
Drug class
Coagulation cascade peptide / substrate
Status
Research use only
Catalog code
THRO-022
Also known as
THRO-022
Reviewed
2026-06-01 · Kindr Health Clinical Team

What Thrombin substrate is studied for

  • Chromogenic protease-activity assays
  • PAR (protease-activated receptor) signaling studies
  • Antithrombotic and anticoagulant screening
  • Fibrinolysis and clot-lysis kinetics

Mechanism of action

Thrombin substrate sits within the Coagulation research class (CPC reference THRO-022). Coagulation peptides act either as chromogenic / fluorogenic substrates for thrombin, FXa, FVIIa, plasmin, and related proteases, or as inhibitors and receptor ligands (e.g. PAR-1/4 activators) that dissect specific cascade nodes. Investigators typically incorporate Thrombin substrate as a reference standard, tool ligand, or substrate in the assay contexts listed above. Read on kinetic plate readers at 405 nm (pNA) or fluorescence (AMC / MCA) endpoints.

Frequently asked questions

What is Thrombin substrate?

Thrombin substrate (CPC catalog code THRO-022) is a synthetic coagulation cascade peptide / substrate in the coagulation category. It is provided as a lyophilized ~1 mg vial for in-vitro research use only.

What is Thrombin substrate studied for?

Published and internal research programs use Thrombin substrate as a reference standard in coagulation workflows — for example, chromogenic protease-activity assays and par (protease-activated receptor) signaling studies. Human clinical evidence is not established.

Is Thrombin substrate FDA-approved for human use?

No. Thrombin substrate is a research-grade reference peptide and is not approved by the FDA or any national regulator for human or veterinary therapeutic use. It is offered exclusively for in-vitro laboratory research and does not ship to the United States for consumer use.

How is Thrombin substrate typically used in the lab?

In a coagulation workflow, Thrombin substrate is reconstituted in sterile buffer or DMSO (solubility-dependent) and applied in the researcher's chosen assay format. Read on kinetic plate readers at 405 nm (pNA) or fluorescence (AMC / MCA) endpoints.

How should Thrombin substrate be stored?

Lyophilized peptide stable at −20 °C. Reconstituted stocks are typically kept at 4 °C for short assays. Follow your institution's standard operating procedures for handling synthetic peptides.

Where does the Thrombin substrate product page point to?

This kindr reference page mirrors CPC Scientific's catalog metadata for THRO-022. The upstream reference sheet — including sequence, purity, MW, and application notes where published — is linked from the buy panel. All orders placed on kindr Peptides ship internationally under research-use terms only.

What quality specifications apply to Thrombin substrate?

Research-grade peptides in the CPC catalog are synthesized by solid-phase peptide synthesis (SPPS), purified by preparative RP-HPLC, and characterized by analytical HPLC and mass spectrometry. Typical purity is ≥95%; certificate of analysis is available on request.

Internal reference sheetOpen the Thrombin substrate physicochemical & handling reference →Upstream reference sheetView CPC Scientific catalog page for THRO-022 →Add to cart · International research catalogBuy Thrombin substrate in the kindr Peptides Shop →

Related peptides in Coagulation

Thrombin Receptor Peptide LigandResearch-grade coagulation · CPC THRO-007
View details
Thrombin Sensitive Peptide (Acid)Research-grade coagulation · CPC THRO-001
View details
Thrombin Sensitive Peptide (Amide)Research-grade coagulation · CPC THRO-008
View details
Hexahydro peptideResearch-grade coagulation · CPC THRO-021
View details
Hemoglobin (Hb) (64-76)Research-grade coagulation · CPC THRO-003
View details
Scrambled TRAP FragmentResearch-grade coagulation · CPC THRO-006
View details

Continue across the Kindr entity graph

Related evidence, peptides, and clinical tools on the same topic.

Research & medical disclosure. This page is educational reference content reviewed by a licensed physician. It is not medical advice and does not establish a clinician–patient relationship. Peptides offered on the kindr Peptides Shop are sold for in vitro laboratory research purposes only and ship internationally — not to the United States. For U.S. clinical care, use the kindr Longevity intake.