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Growth Hormone Axis · GHRH analog + GH secretagogue (compounded)

CJC-1295 + Ipamorelin

Research use · ships internationally
$60.00 / 5mg blend
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CJC-1295 + Ipamorelin reference vial
Drug class
GHRH analog + GH secretagogue (compounded)
Status
Compounded (503A)
Reviewed
2026-06-01 · Kindr Health Clinical Team

What CJC-1295 + Ipamorelin is studied for

  • Growth hormone axis support
  • Sleep quality and slow-wave sleep
  • Body composition and recovery
  • Adult IGF-1 optimization (off-label)

Mechanism of action

CJC-1295 (mod-GRF 1-29 or DAC variant) binds GHRH receptors to amplify endogenous GH release. Ipamorelin binds the ghrelin/GHSR receptor to trigger a clean GH pulse — selectively, without cortisol or prolactin rise (unlike older GHRPs).

Frequently asked questions

How is CJC-1295 + Ipamorelin dosed?

Typical research dosing is 100–300 mcg of each, subcutaneously, 1–3x daily — most commonly at bedtime to align with the largest natural GH pulse. Always under clinician supervision.

Will it shut down natural GH?

Unlike exogenous HGH, GHRH + GHRP combinations work with the pituitary, preserving negative-feedback safety. Cycling is still commonly recommended.

What is the difference between CJC with DAC and no DAC?

No DAC ("Mod GRF 1-29") has a short half-life — clean pulses. With DAC (drug affinity complex) extends half-life to ~8 days, producing sustained GH elevation rather than pulses. Most clinical protocols favor no-DAC for safety.

Side effects?

Injection-site reactions, transient flushing, increased appetite, occasional tingling. Long-term human safety data is limited.

Clinical guideRead the full CJC-1295 + Ipamorelin clinical guide →Add to cart · International research catalogBuy CJC-1295 + Ipamorelin in the kindr Peptides Shop →
Frequently stacked with · Save 15%

Build the CJC-1295 + Ipamorelin protocol stack

Research protocols commonly pair CJC-1295 + Ipamorelin with the peptides below. Add all three vials to unlock the bundle discount at checkout.

This peptide
CJC-1295 + Ipamorelin
$60.00
+ Add
Tesamorelin
GHRH analog studied for visceral fat reduction and body composition.
$95.00
+ Add
Ipamorelin
Selective GH secretagogue — clean pulse, no cortisol or prolactin rise.
$40.00
$195.00 $165.75
You save $29.25 on the stack
Add all 3 to cart →

Related peptides in Growth Hormone Axis

CJC-1295 (No DAC)Short-acting GHRH analog — clean pulsatile GH release.
View details
CJC-1295 with DACLong-acting GHRH analog with drug affinity complex for sustained GH support.
View details
IpamorelinSelective GH secretagogue — clean pulse, no cortisol or prolactin rise.
View details
TesamorelinGHRH analog studied for visceral fat reduction and body composition.
View details
SermorelinA gentler way to support your natural GH rhythm.
View details
HexarelinPotent GH secretagogue studied for cardiac and growth hormone axis support.
View details

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Research & medical disclosure. This page is educational reference content reviewed by a licensed physician. It is not medical advice and does not establish a clinician–patient relationship. Peptides offered on the kindr Peptides Shop are sold for in vitro laboratory research purposes only and ship worldwide, including the United States. For U.S. clinical care, use the kindr Longevity intake.