We use cookies to analyze site usage and improve your experience. You can accept all, reject non-essential, or customize. See our Privacy Policy.
Hormone Replacement Therapy
Compounded hormone therapy prescribed by board-certified menopause specialists — estradiol, progesterone, testosterone, and more. Medications included. Free shipping. Starting at $79/mo.
Licensed in all 50 states · Medications included · Free shipping
Medically reviewed by Dr. Ana Lisa Carr, MD, MBA
Board-Certified Family Medicine Physician · Lead Provider / Medical Reviewer
NPI 1689841744 · Last reviewed: May 10, 2026
What it is
Hormone replacement therapy — HRT — restores the estrogen, progesterone, and sometimes testosterone that the body produces less of during menopause. When these hormones decline, symptoms follow rapidly and often severely: hot flashes, night sweats, sleep disruption, brain fog, mood changes, low libido, and vaginal dryness.
HRT is the most clinically effective treatment for menopausal symptoms and has been supported by decades of research. The North American Menopause Society, ACOG, and the Endocrine Society all recommend HRT as the first-line treatment for symptomatic menopause in healthy women under 60 or within 10 years of menopause onset.
At Kindr we prescribe compounded HRT — meaning your medication is custom-formulated to your exact dosage by our FDA-registered compounding pharmacy. Not a fixed-dose commercial product that may not match your body's specific needs. Your dose. Your delivery method. Your protocol.
The science
Estrogen is involved in over 400 functions in the female body. It regulates temperature control — which is why hot flashes happen when it drops. It modulates serotonin and dopamine — which is why mood changes and anxiety spike during menopause. It maintains collagen production, bone density, cardiovascular function, cognitive clarity, and metabolic regulation.
Progesterone balances estrogen, protects the uterine lining, supports sleep quality, and has a calming effect on the nervous system. When both decline together — the effect is systemic.
Testosterone — often overlooked in women — drives libido, energy, cognitive sharpness, and muscle tone. Low testosterone in menopausal women is extremely common and almost universally undertreated.
What we prescribe
The primary estrogen. Most effective treatment for hot flashes, night sweats, vaginal symptoms, and bone density protection.
Transdermal cream · Patch · Gel · Oral · Vaginal ring
Prescribed alongside estrogen for women with a uterus. Protects the uterine lining and significantly improves sleep quality.
Oral capsule · Topical cream
Low-dose testosterone for libido, energy, cognitive clarity, and muscle tone.
Topical cream · Gel
Targeted low-dose estrogen for vaginal dryness, painful intimacy, and urinary symptoms — minimal systemic absorption.
Cream · Ring · Suppository
Estrogen + progesterone in a single custom-compounded formulation tailored to your symptom profile and delivery preference.
Evidence-based alternatives including SSRIs, SNRIs, gabapentin, and ospemifene for women who cannot or prefer not to use HRT.
Who it's for
Kindr HRT is clinically appropriate for women experiencing:
If you checked three or more — you deserve a clinical conversation. Your Kindr provider will determine whether HRT is appropriate for your individual health history.
What to expect
Tell us about your symptoms, cycle history, personal and family medical history, current medications, and health goals. Our intake is more thorough than most in-person appointments.
A board-certified menopause specialist reviews your full intake. They build your personalized HRT protocol — the right hormones, the right delivery method, the right starting dose for your body.
Your prescription goes to our FDA-registered compounding pharmacy. Your custom-formulated medication is prepared to your exact dose and ships free to your door within 3–5 business days.
Menopause is not a fixed state. Your hormones shift and your protocol shifts with them. Your provider stays with you — check-ins, adjustments, and refills all included in your monthly plan.
Clinical evidence
Kindr HRT protocols are built on current clinical evidence — not outdated guidelines.
Finding
HRT is the most effective treatment for menopausal vasomotor symptoms (hot flashes and night sweats).
Finding
When initiated within 10 years of menopause or before age 60, HRT reduces cardiovascular risk and all-cause mortality.
Finding
Estrogen therapy significantly reduces bone loss and fracture risk in menopausal women.
Source: ACOG Practice Bulletin — Management of Menopausal Symptoms
Finding
Testosterone therapy in postmenopausal women improves sexual function and energy.
Medically reviewed
Medically reviewed by Dr. Ana Lisa Carr, MD, MBA
Board-Certified Family Medicine Physician · Lead Provider / Medical Reviewer
NPI 1689841744 · Last reviewed: May 10, 2026
This page has been reviewed for clinical accuracy against current NAMS, ACOG, and NIH guidelines by a board-certified physician.
FAQ
For most healthy women under 60 or within 10 years of menopause onset, HRT is safe and effective. The Women's Health Initiative findings that previously cast doubt on HRT have been substantially re-analyzed and reinterpreted by NAMS, ACOG, and the Endocrine Society. Your Kindr provider conducts a full personal and family medical history review and individualizes risk-benefit assessment — HRT is never prescribed as a one-size-fits-all decision.
Commercial HRT comes in fixed doses and fixed combinations. Compounded HRT is prepared by a state-licensed, FDA-registered pharmacy to the exact dose, ratio, and delivery method your provider prescribes. This allows protocols that match your specific symptom profile and biology. Compounded medications are not FDA-approved drug products.
Personal history of estrogen-receptor-positive breast cancer is generally a contraindication to systemic HRT. Your Kindr provider will review your oncology history in detail and discuss non-hormonal options such as SSRIs, SNRIs, gabapentin, or local non-estrogen vaginal therapies that may safely improve symptoms. Always coordinate with your oncology team.
Most women notice improvement in hot flashes and sleep within 4–6 weeks of starting an appropriate dose. Mood, libido, and cognitive symptoms often take 8–12 weeks to fully respond. Vaginal symptoms may improve in 2–4 weeks with local estrogen. Dose optimization typically continues for 3 months until your provider confirms the right protocol for you.
Yes. Many women in perimenopause benefit from HRT while still cycling. The protocol — particularly the progesterone component — is designed differently for perimenopausal women than for postmenopausal women. Your Kindr provider will tailor your regimen to your cycle pattern and symptoms.
Symptoms typically return when HRT is discontinued — particularly hot flashes and sleep disruption. Stopping is a personal decision made with your provider. If you do choose to stop, your provider can taper you down gradually to minimize rebound symptoms. There is no medical requirement to stop HRT at a specific age.
Yes — at the low physiologic doses appropriate for women. Testosterone is one of the most undertreated hormones in menopausal women. The Endocrine Society endorses low-dose testosterone for hypoactive sexual desire disorder in postmenopausal women. Kindr providers monitor levels and adjust dosing to keep you in the female physiologic range.
Kindr operates on a flat monthly membership that includes provider care and most medications — no insurance billing. Members can submit superbills to their insurance for potential reimbursement. Most patients find Kindr is less expensive than insurance copays and pharmacy costs combined.
Sources & references
Related services
Compounded semaglutide or tirzepatide — coordinated with your HRT for results neither treatment achieves alone.
Read about GLP-1 Weight Care →
At-home hormone panel — reviewed by your provider in context of your symptoms, not just a number on a reference range.
Read about Hormone Lab Testing →
Specialized care for women in transition — starting as early as 35. Providers who don't dismiss you as too young.
Read about Perimenopause Care →
Personalized care, board-certified providers, all 50 states.
kindr Health is a telehealth platform. Prescription medications require clinical evaluation and provider approval. Compounded medications are prepared by state-licensed, FDA-registered pharmacies and are not FDA-approved drug products. Individual results vary. Not an emergency service. For emergencies call 911. HIPAA Compliant · LegitScript Certification pending · Licensed in all 50 states.