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Kindr Health Medication Center
Hormone therapy, nonhormonal hot-flash options, vaginal and sexual health treatments, GLP-1 medicines, and healthy-aging research. Each guide separates FDA-approved uses from off-label use and unproven claims. An educational page is not an offer to prescribe.
Estradiol in every form, progesterone, combined products, and testosterone education.
Hormone therapy
Patches, gels, creams (e.g. Climara, Divigel, Estrogel)
Bioidentical estrogen — first-line treatment for hot flashes, night sweats, vaginal dryness, and bone protection.
Status: FDA-approved
Read about Estradiol →
Hormone therapy
Prometrium, generic micronized progesterone
Bioidentical progesterone — required for endometrial protection in women with a uterus on estrogen, and a meaningful sleep aid.
Status: FDA-approved
Read about Micronized Progesterone →
Hormone therapy
Compounded transdermal cream
Low-dose testosterone for selected women with low libido, low energy, or persistent post-menopausal "flatness" despite estrogen.
Status: Off-label for women in the U.S.
Read about Testosterone (low-dose, female-physiologic) →
Progestin-only contraceptive (perimenopause)
Drospirenone 4 mg — progestin-only pill
A 24/4 progestin-only pill with antiandrogenic and anti-mineralocorticoid activity — estrogen-free contraception for perimenopausal women, with a more forgiving missed-pill window than older POPs.
Status: FDA-approved for contraception
Read about Slynd →
Hormone therapy
Custom-formulated by FDA-registered 503A compounding pharmacies
Custom-formulated bioidentical hormone therapy prepared to your exact dose by an FDA-registered compounding pharmacy.
Status: Compounded; not FDA-approved
Read about Compounded HRT →
Hormone therapy — brand
Estradiol transdermal patch (once-weekly)
The Climara estradiol patch is a once-weekly transdermal estrogen — the longest-wear FDA-approved estrogen patch for menopause hot flashes, night sweats, vaginal dryness, and osteoporosis prevention.
Status: FDA-approved
Read about Climara →
Hormone therapy — brand
Estradiol transdermal patch (twice-weekly, smallest)
The smallest FDA-approved estradiol patch — twice-weekly delivery in a fingertip-sized patch.
Status: FDA-approved
Read about Minivelle →
Hormone therapy — brand
Conjugated equine estrogens — oral tablet
The original conjugated estrogen tablet — a mix of estrogens derived from pregnant mare urine. Largely supplanted by bioidentical transdermal estradiol.
Status: FDA-approved
Read about Premarin →
Hormone therapy — brand (combined)
Estradiol + norethindrone acetate transdermal patch
CombiPatch is a twice-weekly combined HRT patch delivering bioidentical estradiol plus norethindrone acetate — estrogen and progestin in a single patch for women with a uterus.
Status: FDA-approved
Read about CombiPatch →
Hormone therapy — brand (combined)
Estradiol + norethindrone acetate oral tablet
Activella is a once-daily combined oral HRT tablet — bioidentical estradiol plus norethindrone acetate — for postmenopausal women with a uterus.
Status: FDA-approved
Read about Activella →
Hormone therapy — brand (combined)
Estradiol + levonorgestrel weekly patch
Once-weekly combined estradiol-levonorgestrel patch — estrogen plus progestin in one patch.
Status: FDA-approved (estrogen plus progestin, for people with a uterus)
Read about Climara Pro →
Hormone therapy · Transdermal
Transdermal estradiol — Climara, Vivelle-Dot, Minivelle, Alora, Estraderm, Menostar, Dotti
The estrogen patch delivers bioidentical estradiol through the skin — the form of HRT most major guidelines (NAMS, Endocrine Society) consider first-line because it bypasses the liver and carries a lower clot risk than oral estrogen.
Status: FDA-approved products (form guide)
Read about Estrogen Patch →
Hormone therapy
Activella, CombiPatch, Climara Pro, Prempro, Bijuva, Prefest
Estrogen plus progestogen products for people with a uterus, compared by ingredient, form, and current label.
Status: FDA-approved products (comparison guide)
Read about Combined hormone therapy →
Hormone therapy
Duavee
Estrogen paired with a SERM instead of a progestin for people with a uterus.
Status: FDA-approved for hot flashes and osteoporosis prevention
Read about Conjugated estrogens/bazedoxifene →
FDA-approved and off-label options for hot flashes, clearly labeled by evidence.
Non-hormonal
Brisdelle (low-dose, FDA-approved for hot flashes)
The only SSRI with FDA approval specifically for moderate-to-severe vasomotor symptoms — useful when HRT is not an option.
Status: FDA-approved at 7.5 mg for hot flashes (Brisdelle)
Read about Paroxetine →
Non-hormonal
Veozah
Non-hormonal NK3 receptor antagonist — the newest mechanism for hot flashes, FDA-approved in 2023.
Status: FDA-approved for menopause vasomotor symptoms
Read about Fezolinetant →
Nonhormonal
Lynkuet
Dual NK1/NK3 receptor antagonist taken at bedtime for moderate-to-severe menopause hot flashes.
Status: FDA-approved for menopause vasomotor symptoms
Read about Elinzanetant →
Off-label nonhormonal
Neurontin
Older medicines sometimes used off-label for hot flashes, rated by evidence strength.
Status: Off-label for hot flashes
Read about Gabapentin, oxybutynin & clonidine →
Treatments for genitourinary syndrome of menopause, dryness, and painful sex.
Hormone therapy (local)
Estring, Vagifem, Imvexxy, Estrace cream
Low-dose estrogen applied locally to vaginal tissue — minimal systemic absorption, highly effective for genitourinary symptoms.
Status: FDA-approved
Read about Vaginal Estrogen →
Vaginal estrogen — brand
Estradiol vaginal ring (low-dose, 90 days)
Estring is a low-dose estradiol vaginal ring — one ring releases 7.5 mcg/day for 90 days for genitourinary syndrome of menopause (vaginal dryness, painful sex, recurrent UTIs).
Status: FDA-approved
Read about Estring →
Local (vaginal) estrogen
Estrace Cream, Premarin Cream (CEE), generic estradiol vaginal cream 0.01%
Low-dose vaginal estrogen cream — the first-line, FDA-approved treatment for painful sex, vaginal dryness, and recurrent UTIs from genitourinary syndrome of menopause (GSM).
Status: FDA-approved
Read about Estradiol Vaginal Cream →
Sexual & intimate health
Osphena
Daily oral SERM for menopause-related painful sex and vaginal dryness.
Status: FDA-approved for dyspareunia and vaginal dryness
Read about Ospemifene →
Sexual & intimate health
Intrarosa
Nightly vaginal DHEA insert for menopause-related painful sex.
Status: FDA-approved for dyspareunia
Read about Prasterone →
GLP-1 and related medicines. These are not menopause treatments.
GLP-1 weight care
Wegovy, Ozempic
Weekly GLP-1 injection for chronic weight management, used adjunctively in menopausal weight changes when appropriate.
Status: FDA-approved (indication varies by product)
Read about Semaglutide →
GLP-1 weight care
Zepbound, Mounjaro
Dual GIP/GLP-1 receptor agonist — currently the most effective FDA-approved weight medication available.
Status: FDA-approved (indication varies by product)
Read about Tirzepatide →
GLP-1 & metabolic
Foundayo
FDA-approved oral small-molecule GLP-1 receptor agonist for chronic weight management in a defined adult population.
Status: FDA-approved for chronic weight management
Read about Orforglipron →
GLP-1 & metabolic
Saxenda, Victoza
Daily GLP-1 injection; Saxenda and Victoza carry different indications.
Status: FDA-approved (indication varies by product)
Read about Liraglutide →
Comparison
Semaglutide products
Same ingredient, different FDA-approved products and indications.
Status: Comparison guide
Read about Ozempic vs Wegovy vs Rybelsus →
Comparison
Tirzepatide products
How the two tirzepatide products differ in approved use.
Status: Comparison guide
Read about Zepbound vs Mounjaro →
Medicines studied for aging, with approved uses separated from unproven claims.
Aging research
Glucophage
Type 2 diabetes medicine studied in aging research; longevity benefit unproven.
Status: FDA-approved for type 2 diabetes; longevity use unproven
Read about Metformin →
Aging research
Rapamune
mTOR inhibitor with transplant and rare-disease approvals; longevity evidence is preclinical and early human.
Status: Not FDA-approved for longevity
Read about Rapamycin (sirolimus) →
A licensed healthcare professional can review your history, current medicines, symptoms, and goals to discuss appropriate options. A prescription is not guaranteed.
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