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Medications

Every medication. Plain English. Real evidence.

No marketing copy. Each medication explained the way our clinicians explain it in a visit.

Hormone therapy

Estradiol

Patches, gels, creams (e.g. Climara, Divigel, Estrogel)

Bioidentical estrogen — first-line treatment for hot flashes, night sweats, vaginal dryness, and bone protection.

Read about Estradiol →

Hormone therapy

Micronized Progesterone

Prometrium, generic micronized progesterone

Bioidentical progesterone — required for endometrial protection in women with a uterus on estrogen, and a meaningful sleep aid.

Read about Micronized Progesterone →

Hormone therapy

Testosterone (low-dose, female-physiologic)

Compounded transdermal cream

Low-dose testosterone for selected women with low libido, low energy, or persistent post-menopausal "flatness" despite estrogen.

Read about Testosterone (low-dose, female-physiologic) →

GLP-1 weight care

Semaglutide

Wegovy, Ozempic

Weekly GLP-1 injection for chronic weight management, used adjunctively in menopausal weight changes when appropriate.

Read about Semaglutide →

GLP-1 weight care

Tirzepatide

Zepbound, Mounjaro

Dual GIP/GLP-1 receptor agonist — currently the most effective FDA-approved weight medication available.

Read about Tirzepatide →

Non-hormonal

Paroxetine

Brisdelle (low-dose, FDA-approved for hot flashes)

The only SSRI with FDA approval specifically for moderate-to-severe vasomotor symptoms — useful when HRT is not an option.

Read about Paroxetine →

Non-hormonal

Fezolinetant

Veozah

Non-hormonal NK3 receptor antagonist — the newest mechanism for hot flashes, FDA-approved in 2023.

Read about Fezolinetant →

Hormone therapy (local)

Vaginal Estrogen

Estring, Vagifem, Imvexxy, Estrace cream

Low-dose estrogen applied locally to vaginal tissue — minimal systemic absorption, highly effective for genitourinary symptoms.

Read about Vaginal Estrogen →

Hormone therapy

Compounded HRT

Custom-formulated by FDA-registered 503A compounding pharmacies

Custom-formulated bioidentical hormone therapy prepared to your exact dose by an FDA-registered compounding pharmacy.

Read about Compounded HRT →

Hormone therapy — brand

Climara

Estradiol transdermal patch (once-weekly)

Once-weekly estradiol patch. The longest-wear FDA-approved transdermal estrogen for menopause symptoms.

Read about Climara →

Hormone therapy — brand

Vivelle-Dot

Estradiol transdermal patch (twice-weekly)

Small, discrete twice-weekly estradiol patch. One of the most prescribed transdermal HRT brands in the U.S.

Read about Vivelle-Dot →

Hormone therapy — brand

Minivelle

Estradiol transdermal patch (twice-weekly, smallest)

The smallest FDA-approved estradiol patch — twice-weekly delivery in a fingertip-sized patch.

Read about Minivelle →

Hormone therapy — brand

EstroGel

Estradiol transdermal gel (daily)

Daily transdermal estradiol gel — applied to the arm. Flexible dosing without a patch.

Read about EstroGel →

Hormone therapy — brand

Divigel

Estradiol transdermal gel single-dose packets

Single-dose estradiol gel packets — precise daily dosing applied to the thigh.

Read about Divigel →

Hormone therapy — brand

Estrace

Oral estradiol tablets / vaginal cream

Bioidentical oral estradiol tablet and a separate vaginal cream — long-established brand formulations.

Read about Estrace →

Hormone therapy — brand

Alora

Twice-weekly estradiol patch

Twice-weekly transdermal estradiol patch in 0.025–0.1 mg/day strengths.

Read about Alora →

Hormone therapy — brand

Estraderm

Twice-weekly estradiol reservoir patch

Reservoir-style estradiol patch — one of the original transdermal HRT options.

Read about Estraderm →

Hormone therapy — brand

Menostar

Weekly ultra-low-dose estradiol patch

Once-weekly ultra-low-dose (0.014 mg/day) estradiol patch indicated for osteoporosis prevention.

Read about Menostar →

Hormone therapy — brand

Dotti

Twice-weekly estradiol patch (generic Vivelle-Dot)

Authorized generic of Vivelle-Dot — twice-weekly small matrix estradiol patch.

Read about Dotti →

Hormone therapy — brand

Premarin

Conjugated equine estrogens — oral tablet

The original conjugated estrogen tablet — a mix of estrogens derived from pregnant mare urine. Largely supplanted by bioidentical transdermal estradiol.

Read about Premarin →

Hormone therapy — brand

Femtrace

Estradiol acetate — oral tablet

Bioidentical oral estradiol (as estradiol acetate) — once-daily tablet.

Read about Femtrace →

Hormone therapy — brand

Elestrin

Estradiol gel — pump applicator

Low-dose transdermal estradiol gel applied to the upper arm via metered pump.

Read about Elestrin →

Hormone therapy — brand

Estrasorb

Estradiol topical emulsion

Transdermal estradiol topical emulsion in single-use packets applied to the legs.

Read about Estrasorb →

Hormone therapy — brand

Prometrium

Micronized progesterone — oral capsule

Brand-name oral micronized progesterone — bioidentical, taken at bedtime for endometrial protection and sleep benefit.

Read about Prometrium →

Hormone therapy — brand

Crinone

Progesterone vaginal gel

Bioidentical progesterone vaginal gel — primarily used in fertility treatment but occasionally in HRT for patients intolerant of oral progesterone.

Read about Crinone →

Hormone therapy — brand

Endometrin

Progesterone vaginal insert

Bioidentical progesterone vaginal insert — primarily used in fertility treatment.

Read about Endometrin →

Vaginal estrogen — brand

Estring

Estradiol vaginal ring (low-dose, 90 days)

Low-dose estradiol vaginal ring — one ring lasts 90 days for genitourinary syndrome of menopause.

Read about Estring →

Vaginal estrogen — brand

Vagifem

Estradiol vaginal tablet (10 mcg)

Low-dose 10 mcg estradiol vaginal tablet inserted twice weekly after a loading phase.

Read about Vagifem →

Vaginal estrogen — brand

Imvexxy

Estradiol vaginal softgel insert

Applicator-free 4 mcg or 10 mcg estradiol vaginal softgel — the lowest-dose vaginal estradiol option.

Read about Imvexxy →

Vaginal estrogen — brand

Premarin Vaginal

Conjugated estrogens vaginal cream

Conjugated equine estrogen vaginal cream — long-established option for genitourinary syndrome of menopause.

Read about Premarin Vaginal →

Vaginal estrogen — brand

Yuvafem

Estradiol vaginal tablet (Vagifem generic)

Authorized generic of Vagifem — 10 mcg estradiol vaginal tablet.

Read about Yuvafem →

Hormone therapy — brand (combined)

CombiPatch

Estradiol + norethindrone patch

Twice-weekly combined estradiol-norethindrone patch — estrogen plus progestin in one patch.

Read about CombiPatch →

Hormone therapy — brand (combined)

Climara Pro

Estradiol + levonorgestrel weekly patch

Once-weekly combined estradiol-levonorgestrel patch — estrogen plus progestin in one patch.

Read about Climara Pro →

Hormone therapy — brand (combined)

Prefest

Estradiol + norgestimate oral tablet (pulsed)

Pulsed combined oral HRT — estradiol every day, norgestimate every other 3 days.

Read about Prefest →

Hormone therapy · Transdermal

Estrogen Patch

Transdermal estradiol — Climara, Vivelle-Dot, Minivelle, Alora, Estraderm, Menostar, Dotti

The estrogen patch delivers bioidentical estradiol through the skin — the form of HRT most major guidelines (NAMS, Endocrine Society) consider first-line because it bypasses the liver and carries a lower clot risk than oral estrogen.

Read about Estrogen Patch →

Hormone therapy · Topical & vaginal

Estrogen Cream

Topical and vaginal estradiol — EstroGel, Divigel, Elestrin, Estrace Cream, Premarin Vaginal Cream

Estrogen creams cover two distinct uses: systemic transdermal estradiol creams and gels for whole-body menopause symptoms, and low-dose vaginal estrogen creams for genitourinary symptoms (GSM) like vaginal dryness and painful sex.

Read about Estrogen Cream →

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