We use cookies to analyze site usage and improve your experience. You can accept all, reject non-essential, or customize. See our Privacy Policy.
Reference sheet · Ion Channel Toxins · CPC catalog code CHAT-001
Reference standards in the Ion Channel Toxins class are typically shipped as lyophilized powder and stored desiccated at −20 °C protected from light. Once reconstituted in bacteriostatic water or the assay-appropriate buffer, aliquot and store at −80 °C to minimize freeze–thaw cycles. Confirm handling requirements against your institutional biosafety and radiation protocols before use.
Charybdotoxin sits within the Ion Channel Toxins research class (CPC reference CHAT-001). Ion-channel toxins bind with sub-nanomolar affinity to specific channel subtypes (Kv, Nav, Cav, NMDA), stabilizing closed, open, or inactivated states. They are among the most selective tools available for dissecting channel function. Investigators typically incorporate Charybdotoxin as a reference standard, tool ligand, or substrate in the assay contexts listed above. Manual or automated patch clamp (QPatch, Patchliner) and radioligand binding are the standard readouts.
Charybdotoxin (CPC catalog code CHAT-001) is a synthetic ion-channel toxin (research reagent) in the ion channel toxins category. It is provided as a lyophilized ~1 mg vial for in-vitro research use only.
Published and internal research programs use Charybdotoxin as a reference standard in ion channel toxins workflows — for example, patch-clamp characterization of channel subtypes and neuronal excitability and pain-circuit research. Human clinical evidence is not established.
No. Charybdotoxin is a research-grade reference peptide and is not approved by the FDA or any national regulator for human or veterinary therapeutic use. It is offered exclusively for in-vitro laboratory research and does not ship to the United States for consumer use.
In a ion channel toxins workflow, Charybdotoxin is reconstituted in sterile buffer or DMSO (solubility-dependent) and applied in the researcher's chosen assay format. Manual or automated patch clamp (QPatch, Patchliner) and radioligand binding are the standard readouts.
Other reference standards in the same class — commonly cross-referenced during assay design and comparator selection.