Knowledge Graph · Condition
Breast Cancer
Cancer that forms in the cells of the breasts.
Authoritative sources
Evidence base
Randomized Controlled Trial · 2004 · Landmark
Effects of Conjugated Equine Estrogen in Postmenopausal Women with Hysterectomy
JAMA · Anderson GL, Limacher M, Assaf AR, et al.
For women without a uterus, estrogen-only therapy showed a much more favorable risk profile than the combined therapy arm.
Randomized Controlled Trial · 2002 · Landmark
Risks and Benefits of Estrogen Plus Progestin in Healthy Postmenopausal Women
JAMA · Rossouw JE, Anderson GL, Prentice RL, et al. (Writing Group for the Women's Health Initiative)
The Women's Health Initiative was the landmark trial that reshaped how doctors prescribe hormone therapy after menopause. Later re-analyses showed the risk profile is very different for women who start HRT closer to menopause.
Randomized Controlled Trial · 2026
Trastuzumab Deruxtecan plus Pertuzumab for HER2-Positive Metastatic Breast Cancer
The New England journal of medicine · Tolaney SM, Jiang Z, Zhang Q, Barroso-Sousa R, et al.
Randomized Controlled Trial · 2025
Imlunestrant with or without Abemaciclib in Advanced Breast Cancer
The New England journal of medicine · Jhaveri KL, Neven P, Casalnuovo ML, Kim SB, et al.
Randomized Controlled Trial · 2024
Overall Survival with Pembrolizumab in Early-Stage Triple-Negative Breast Cancer
The New England journal of medicine · Schmid P, Cortes J, Dent R, McArthur H, et al.
Randomized Controlled Trial · 2024
Trastuzumab Deruxtecan after Endocrine Therapy in Metastatic Breast Cancer
The New England journal of medicine · Bardia A, Hu X, Dent R, Yonemori K, et al.
Randomized Controlled Trial · 2024
Ribociclib plus Endocrine Therapy in Early Breast Cancer
The New England journal of medicine · Slamon D, Lipatov O, Nowecki Z, McAndrew N, et al.
Randomized Controlled Trial · 2023
Capivasertib in Hormone Receptor-Positive Advanced Breast Cancer
The New England journal of medicine · Turner NC, Oliveira M, Howell SJ, Dalenc F, et al.
Randomized Controlled Trial · 2022
Journal of clinical oncology : official journal of the American Society of Clinical Oncology · Bidard FC, Kaklamani VG, Neven P, Streich G, et al.
Randomized Controlled Trial · 2022
Trastuzumab Deruxtecan in Previously Treated HER2-Low Advanced Breast Cancer
The New England journal of medicine · Modi S, Jacot W, Yamashita T, Sohn J, et al.
Randomized Controlled Trial · 2022
Trastuzumab Deruxtecan versus Trastuzumab Emtansine for Breast Cancer
The New England journal of medicine · Cortés J, Kim SB, Chung WP, Im SA, et al.
Randomized Controlled Trial · 2021
Sacituzumab Govitecan in Metastatic Triple-Negative Breast Cancer
The New England journal of medicine · Bardia A, Hurvitz SA, Tolaney SM, Loirat D, et al.
Where Breast Cancer appears on Kindr Health
Data hub
This page is part of Kindr Health's public Knowledge Graph. Content is for educational purposes only and is not medical advice.