Knowledge Graph · Medication
Tirzepatide
A dual GIP and GLP-1 receptor agonist for type 2 diabetes and obesity.
Authoritative sources
Evidence base
Randomized Controlled Trial · 2022 · Landmark
Tirzepatide Once Weekly for the Treatment of Obesity
New England Journal of Medicine · Jastreboff AM, Aronne LJ, Ahmad NN, et al. (SURMOUNT-1)
The pivotal trial that established tirzepatide (Zepbound / Mounjaro) as the most effective medication studied for weight loss to date.
Phase III Clinical Trial · 2025
Tirzepatide as Compared with Semaglutide for the Treatment of Obesity
The New England journal of medicine · Aronne LJ, Horn DB, le Roux CW, Ho W, et al.
Randomized Controlled Trial · 2025
Tirzepatide for Obesity Treatment and Diabetes Prevention
The New England journal of medicine · Jastreboff AM, le Roux CW, Stefanski A, Aronne LJ, et al.
Randomized Controlled Trial · 2025
Tirzepatide for Heart Failure with Preserved Ejection Fraction and Obesity
The New England journal of medicine · Packer M, Zile MR, Kramer CM, Baum SJ, et al.
Phase III Clinical Trial · 2025
Cardiovascular Outcomes with Tirzepatide versus Dulaglutide in Type 2 Diabetes
The New England journal of medicine · Nicholls SJ, Pavo I, Bhatt DL, Buse JB, et al.
Randomized Controlled Trial · 2024
Tirzepatide for the Treatment of Obstructive Sleep Apnea and Obesity
The New England journal of medicine · Malhotra A, Grunstein RR, Fietze I, Weaver TE, et al.
Randomized Controlled Trial · 2024
JAMA · Aronne LJ, Sattar N, Horn DB, Bays HE, et al.
Systematic Review · 2024
BMJ (Clinical research ed.) · Yao H, Zhang A, Li D, Wu Y, et al.
Randomized Controlled Trial · 2022
Tirzepatide Once Weekly for the Treatment of Obesity
The New England journal of medicine · Jastreboff AM, Aronne LJ, Ahmad NN, Wharton S, et al.
Randomized Controlled Trial · 2021
Tirzepatide versus Semaglutide Once Weekly in Patients with Type 2 Diabetes
The New England journal of medicine · Frías JP, Davies MJ, Rosenstock J, Pérez Manghi FC, et al.
Where Tirzepatide appears on Kindr Health
Data hub
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This page is part of Kindr Health's public Knowledge Graph. Content is for educational purposes only and is not medical advice.