Does HRT cause weight gain?
Trials show HRT users gain less weight than non-users.
The evidence
Multiple RCTs: HRT reduces waist circumference and abdominal fat.
Why women feel bigger
Bloating in first 4-6 weeks is common and resolves.
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Related: FDA peptide review July 2026 briefing · Peptide therapy hub · Longevity service
Written and medically reviewed by the Kindr Health Clinical Team · Published 2026-06-19 · Last reviewed 2026-07-01. Compounded medications are prepared by FDA-registered 503A pharmacies and are not FDA-approved drug products.