Stopping HRT before surgery
Transdermal HRT usually does not need to be stopped; oral may be paused 4 weeks before major surgery.
Clot risk
Oral estrogen doubles VTE risk; transdermal does not.
Practical rule
Ask your surgeon; most allow transdermal to continue.
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Related: FDA peptide review July 2026 briefing · Peptide therapy hub · Longevity service
Written and medically reviewed by the Kindr Health Clinical Team · Published 2026-06-19 · Last reviewed 2026-07-01. Compounded medications are prepared by FDA-registered 503A pharmacies and are not FDA-approved drug products.