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Gynecology \u00b7 Postmenopause

Ovarian cysts after menopause: when to worry

Postmenopausal ovaries are quiet \u2014 new cysts warrant more scrutiny than premenopausal ones. Simple <5cm cysts are usually benign and managed with follow-up ultrasound; complex features change the picture.

Key points

  • Simple cyst <5cm: repeat US 3–6 months
  • Complex features: gyn-oncology
  • CA-125 with caution — nonspecific

Frequently asked questions

Are postmenopausal cysts always cancer?

No — most are benign. But threshold for workup is lower.

What labs help?

CA-125, HE4, ROMA score in complex cases.

When is surgery indicated?

Complex morphology, growth, or elevated tumor markers.

Considering a physician-supervised longevity protocol? Kindr Health evaluates peptide therapy as part of personalized perimenopause and menopause care.

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Related: FDA peptide review July 2026 briefing · Peptide therapy hub · Longevity service

Medically reviewed by Kindr Health Clinical Team · Last reviewed 2026-06-19. Compounded medications are prepared by FDA-registered 503A pharmacies and are not FDA-approved drug products.

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