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Menopause Medications A–Z
Bioidentical estradiol, micronized progesterone, testosterone for women, GLP-1s, and non-hormonal hot-flash options — explained the way our clinicians explain them in a visit. Prescribed online, shipped in all 50 states.
Hormone therapy
Patches, gels, creams (e.g. Climara, Divigel, Estrogel)
Bioidentical estrogen — first-line treatment for hot flashes, night sweats, vaginal dryness, and bone protection.
Read about Estradiol →
Hormone therapy (local)
Estring, Vagifem, Imvexxy, Estrace cream
Low-dose estrogen applied locally to vaginal tissue — minimal systemic absorption, highly effective for genitourinary symptoms.
Read about Vaginal Estrogen →
Hormone therapy — brand
Estradiol transdermal patch (once-weekly)
The Climara estradiol patch is a once-weekly transdermal estrogen — the longest-wear FDA-approved estrogen patch for menopause hot flashes, night sweats, vaginal dryness, and osteoporosis prevention.
Read about Climara →
Hormone therapy — brand
Estradiol transdermal patch (twice-weekly)
Small, discrete twice-weekly estradiol patch. One of the most prescribed transdermal HRT brands in the U.S.
Read about Vivelle-Dot →
Hormone therapy — brand
Estradiol transdermal patch (twice-weekly, smallest)
The smallest FDA-approved estradiol patch — twice-weekly delivery in a fingertip-sized patch.
Read about Minivelle →
Hormone therapy — brand
Estradiol transdermal gel (daily)
Daily transdermal estradiol gel — applied to the arm. Flexible dosing without a patch.
Read about EstroGel →
Hormone therapy — brand
Estradiol transdermal gel single-dose packets
Single-dose estradiol gel packets — precise daily dosing applied to the thigh.
Read about Divigel →
Hormone therapy — brand
Oral estradiol tablets / vaginal cream
Bioidentical oral estradiol tablet and a separate vaginal cream — long-established brand formulations.
Read about Estrace →
Hormone therapy — brand
Twice-weekly estradiol patch
Twice-weekly transdermal estradiol patch in 0.025–0.1 mg/day strengths.
Read about Alora →
Hormone therapy — brand
Twice-weekly estradiol reservoir patch
Reservoir-style estradiol patch — one of the original transdermal HRT options.
Read about Estraderm →
Hormone therapy — brand
Weekly ultra-low-dose estradiol patch
Once-weekly ultra-low-dose (0.014 mg/day) estradiol patch indicated for osteoporosis prevention.
Read about Menostar →
Hormone therapy — brand
Twice-weekly estradiol patch (generic Vivelle-Dot)
Authorized generic of Vivelle-Dot — twice-weekly small matrix estradiol patch.
Read about Dotti →
Hormone therapy — brand
Conjugated equine estrogens — oral tablet
The original conjugated estrogen tablet — a mix of estrogens derived from pregnant mare urine. Largely supplanted by bioidentical transdermal estradiol.
Read about Premarin →
Hormone therapy — brand
Estradiol acetate — oral tablet
Bioidentical oral estradiol (as estradiol acetate) — once-daily tablet.
Read about Femtrace →
Hormone therapy — brand
Estradiol gel — pump applicator
Low-dose transdermal estradiol gel applied to the upper arm via metered pump.
Read about Elestrin →
Hormone therapy — brand
Estradiol topical emulsion
Transdermal estradiol topical emulsion in single-use packets applied to the legs.
Read about Estrasorb →
Vaginal estrogen — brand
Estradiol vaginal ring (low-dose, 90 days)
Estring is a low-dose estradiol vaginal ring — one ring releases 7.5 mcg/day for 90 days for genitourinary syndrome of menopause (vaginal dryness, painful sex, recurrent UTIs).
Read about Estring →
Vaginal estrogen — brand
Estradiol vaginal tablet (10 mcg)
Low-dose 10 mcg estradiol vaginal tablet inserted twice weekly after a loading phase.
Read about Vagifem →
Vaginal estrogen — brand
Estradiol vaginal softgel insert
Applicator-free 4 mcg or 10 mcg estradiol vaginal softgel — the lowest-dose vaginal estradiol option.
Read about Imvexxy →
Vaginal estrogen — brand
Conjugated estrogens vaginal cream
Conjugated equine estrogen vaginal cream — long-established option for genitourinary syndrome of menopause.
Read about Premarin Vaginal →
Vaginal estrogen — brand
Estradiol vaginal tablet (Vagifem generic)
Authorized generic of Vagifem — 10 mcg estradiol vaginal tablet.
Read about Yuvafem →
Hormone therapy — brand (combined)
Estradiol + norethindrone acetate transdermal patch
CombiPatch is a twice-weekly combined HRT patch delivering bioidentical estradiol plus norethindrone acetate — estrogen and progestin in a single patch for women with a uterus.
Read about CombiPatch →
Hormone therapy — brand (combined)
Estradiol + norethindrone acetate oral tablet
Activella is a once-daily combined oral HRT tablet — bioidentical estradiol plus norethindrone acetate — for postmenopausal women with a uterus.
Read about Activella →
Hormone therapy — brand (combined)
Estradiol + levonorgestrel weekly patch
Once-weekly combined estradiol-levonorgestrel patch — estrogen plus progestin in one patch.
Read about Climara Pro →
Hormone therapy — brand (combined)
Estradiol + norgestimate oral tablet (pulsed)
Pulsed combined oral HRT — estradiol every day, norgestimate every other 3 days.
Read about Prefest →
Hormone therapy · Transdermal
Transdermal estradiol — Climara, Vivelle-Dot, Minivelle, Alora, Estraderm, Menostar, Dotti
The estrogen patch delivers bioidentical estradiol through the skin — the form of HRT most major guidelines (NAMS, Endocrine Society) consider first-line because it bypasses the liver and carries a lower clot risk than oral estrogen.
Read about Estrogen Patch →
Hormone therapy · Topical & vaginal
Topical and vaginal estradiol — EstroGel, Divigel, Elestrin, Estrace Cream, Premarin Vaginal Cream
Estrogen creams cover two distinct uses: systemic transdermal estradiol creams and gels for whole-body menopause symptoms, and low-dose vaginal estrogen creams for genitourinary symptoms (GSM) like vaginal dryness and painful sex.
Read about Estrogen Cream →
Local (vaginal) estrogen
Estrace Cream, Premarin Cream (CEE), generic estradiol vaginal cream 0.01%
Low-dose vaginal estrogen cream — the first-line, FDA-approved treatment for painful sex, vaginal dryness, and recurrent UTIs from genitourinary syndrome of menopause (GSM).
Read about Estradiol Vaginal Cream →
Hormone therapy
Prometrium, generic micronized progesterone
Bioidentical progesterone — required for endometrial protection in women with a uterus on estrogen, and a meaningful sleep aid.
Read about Micronized Progesterone →
Hormone therapy — brand
Micronized progesterone — oral capsule
Brand-name oral micronized progesterone — bioidentical, taken at bedtime for endometrial protection and sleep benefit.
Read about Prometrium →
Hormone therapy — brand
Progesterone vaginal gel
Bioidentical progesterone vaginal gel — primarily used in fertility treatment but occasionally in HRT for patients intolerant of oral progesterone.
Read about Crinone →
Hormone therapy — brand
Progesterone vaginal insert
Bioidentical progesterone vaginal insert — primarily used in fertility treatment.
Read about Endometrin →
GLP-1 weight care
Wegovy, Ozempic
Weekly GLP-1 injection for chronic weight management, used adjunctively in menopausal weight changes when appropriate.
Read about Semaglutide →
GLP-1 weight care
Zepbound, Mounjaro
Dual GIP/GLP-1 receptor agonist — currently the most effective FDA-approved weight medication available.
Read about Tirzepatide →
Non-hormonal
Brisdelle (low-dose, FDA-approved for hot flashes)
The only SSRI with FDA approval specifically for moderate-to-severe vasomotor symptoms — useful when HRT is not an option.
Read about Paroxetine →
Non-hormonal
Veozah
Non-hormonal NK3 receptor antagonist — the newest mechanism for hot flashes, FDA-approved in 2023.
Read about Fezolinetant →
A Kindr clinician will match you to the right therapy — bioidentical HRT, GLP-1, non-hormonal, or a combination — based on your history, labs, and goals. Board-certified. All 50 states.
Start your visit →